The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.
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The dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β and IFN-γPorphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's diseaseInteractions between inflammation, sex steroids, and Alzheimer's disease risk factorsMultifaceted interactions between adaptive immunity and the central nervous system.Central Nervous System: (Immunological) Ivory Tower or Not?Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice.Increased tauopathy drives microglia-mediated clearance of beta-amyloid.Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1ΔE9 mice: potential mechanism underlying cognitive impairment.Nitric Oxide: Exploring the Contextual Link with Alzheimer's DiseaseInflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice.HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.Dissecting Amyloid Beta Deposition Using Distinct Strains of the Neurotropic Parasite Toxoplasma gondii as a Novel Tool.MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist.Drugs in Clinical Trials for Alzheimer's Disease: The Major Trends.Cardiolipin in Central Nervous System Physiology and Pathology.Potential importance of B cells in aging and aging-associated neurodegenerative diseases.Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease.Apolipoprotein E4, Gender, Body Mass Index, Inflammation, Insulin Resistance, and Air Pollution Interactions: Recipe for Alzheimer's Disease Development in Mexico City Young Females.Can Better Management of Periodontal Disease Delay the Onset and Progression of Alzheimer's Disease?Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer's diseaseHuman Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease.GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer's disease.Impaired IL-17 Production in Gut-Residing Immune Cells of 5xFAD Mice with Alzheimer's Disease Pathology.Periodontitis, Microbiomes and their Role in Alzheimer's Disease.Impairment of Several Immune Functions and Redox State in Blood Cells of Alzheimer's Disease Patients. Relevant Role of Neutrophils in Oxidative Stress.Systemic immune-checkpoint blockade with anti-PD1 antibodies does not alter cerebral amyloid-β burden in several amyloid transgenic mouse models.Modelling Neurodegenerative Microenvironment Using Cortical Organoids Derived from Human Stem Cells.Early diagnosis of Alzheimer's disease using infrared spectroscopy of isolated blood samples followed by multivariate analyses.Circulating Progenitor Cells Correlate with Memory, Posterior Cortical Thickness, and Hippocampal Perfusion.Can immunotherapy treat neurodegeneration?Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.Immunomodulatory Properties of Carvone Inhalation and Its Effects on Contextual Fear Memory in Mice.Neuroinflammation: Microglia and T Cells Get Ready to Tango.Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.Targeting microglia for the treatment of Alzheimer's Disease.
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P2860
The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The adaptive immune system res ...... odulating microglial function.
@ast
The adaptive immune system res ...... odulating microglial function.
@en
type
label
The adaptive immune system res ...... odulating microglial function.
@ast
The adaptive immune system res ...... odulating microglial function.
@en
prefLabel
The adaptive immune system res ...... odulating microglial function.
@ast
The adaptive immune system res ...... odulating microglial function.
@en
P2093
P2860
P50
P356
P1476
The adaptive immune system res ...... odulating microglial function.
@en
P2093
Alborz Karimzadeh
Anita Lakatos
Edsel M Abud
Gianna M Fote
Hayk Davtyan
Jason G Weinger
Matthew A Inlay
Thomas E Lane
P2860
P304
P356
10.1073/PNAS.1525466113
P407
P577
2016-02-16T00:00:00Z