Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. - Wikidata - awgldk - TriplyDB

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

http://www.wikidata.org/entity/Q36663630

about

CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis X-linked megalocornea caused by mutations in CHRDL1 identifies an essential role for ventroptin in anterior segment development Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors Local network topology in human protein interaction data predicts functional association Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development The role of CCN2 in cartilage and bone development WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity Functions and mechanisms of action of CCN matricellular proteins WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death Fibrosis in diabetes complications: pathogenic mechanisms and circulating and urinary markers Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis Normal growth and development in mice over-expressing the CCN family member WISP3 Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis The CCN family of proteins: structure-function relationships WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair The matricellular protein CCN1 is essential for cardiac development BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation Differential expression of CCN-family members in primary human bone marrow-derived mesenchymal stem cells during osteogenic, chondrogenic and adipogenic differentiation.Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step Wnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritis CCN: core regulatory proteins in the microenvironment that affect the metastasis of hepatocellular carcinoma?Role of endoglin in fibrosis and scleroderma Management of fibrosis: the mesenchymal stromal cells breakthrough Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system Role of bone morphogenetic protein-7 in renal fibrosis Roles for CCN2 in normal physiological processes Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets Mesenchymal Conversion of Mesothelial Cells Is a Key Event in the Pathophysiology of the Peritoneum during Peritoneal Dialysis O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease Mammalian twisted gastrulation is essential for skeleto-lymphogenesis Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene Smad signaling in skeletal development and regeneration.Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage.Matricellular proteins in the trabecular meshwork: review and update.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

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P2860

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

http://www.wikidata.org/entity/Q36663630

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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2002年论文

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2002年论文

@zh-cn

name

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@ast

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@en

type

label

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@ast

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@en

prefLabel

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@ast

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@en

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P1433

Nature Cell Biology

P1476

Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta.

@en

P2093

Bruno Reversade

http://www.w3.org/2001/XMLSchema#string

E M De Robertis

http://www.w3.org/2001/XMLSchema#string

José G Abreu

http://www.w3.org/2001/XMLSchema#string

Nan I Ketpura

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P2860

TGF beta signals through a heteromeric protein kinase receptor complex

Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes

BMP-binding modules in chordin: a model for signalling regulation in the extracellular space

Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily

The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor

A mouse cerberus/Dan-related gene family

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

The thrombospondin type 1 repeat (TSR) superfamily: diverse proteins with related roles in neuronal development.

Connective tissue growth factor: what's in a name?

Ventroptin: a BMP-4 antagonist expressed in a double-gradient pattern in the retina.

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10.1038/NCB826

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8

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4

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12134160

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2387275

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