The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA.
about
The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcriptionThe RNA polymerase I transcription machineryControl of rRNA transcription in Escherichia coliA functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathwayMorphology of nuclear transcriptionPerturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human diseaseRRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template.Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein.Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcriptionSurvey and summary: transcription by RNA polymerases I and III.Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcriptionA step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription.Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor bodyTBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter.UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat.Structure of recombinant rat UBF by electron image analysis and homology modellingThe DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxesUBF activates RNA polymerase I transcription by stimulating promoter escape.rRNA gene silencing and nucleolar dominance: insights into a chromosome-scale epigenetic on/off switchConstruction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division.Stimulation of the mouse rRNA gene promoter by a distal spacer promoter.Site-directed photo-cross-linking of rRNA transcription initiation complexes.Nucleosome binding by the polymerase I transactivator upstream binding factor displaces linker histone H1.Ribosomal chromatin organization.Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling.Involvement of in situ conformation of ribosomal genes and selective distribution of upstream binding factor in rRNA transcriptionEnvironmental signaling through the mechanistic target of rapamycin complex 1: mTORC1 goes nuclear.Topoisomerase IIα promotes activation of RNA polymerase I transcription by facilitating pre-initiation complex formation.Activated levels of rRNA synthesis in fission yeast are driven by an intergenic rDNA region positioned over 2500 nucleotides upstream of the initiation site.Dimerization and HMG box domains 1-3 present in Xenopus UBF are sufficient for its role in transcriptional enhancement.Acanthamoeba castellanii contains a ribosomal RNA enhancer binding protein which stimulates TIF-IB binding and transcription under stringent conditions.HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF.Regulation of ribosomal gene transcription.The first high-mobility-group box of upstream binding factor assembles across-over DNA junction by basic residues.Virtually the entire Xenopus laevis rDNA multikilobase intergenic spacer serves to stimulate polymerase I transcription.A novel transcription initiation factor (TIF), TIF-IE, is required for homogeneous Acanthamoeba castellanii TIF-IB (SL1) to form a committed complex.
P2860
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P2860
The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@ast
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@en
type
label
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@ast
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@en
prefLabel
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@ast
The RNA polymerase I transacti ...... tively supercoil enhancer DNA.
@en
P2860
P356
P1476
The RNA polymerase I transacti ...... itively supercoil enhancer DNA
@en
P2093
C D Putnam
M L Denton
P2860
P304
P356
10.1128/MCB.14.10.6476
P407
P577
1994-10-01T00:00:00Z