Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia.
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The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine AntigensCauses and consequences of coagulation activation in sepsis: an evolutionary medicine perspectiveImmunogenic properties of Streptococcus agalactiae FbsA fragmentsThe Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein ExpressionThe Staphylococcal Biofilm: Adhesins, Regulation, and Host ResponseThrombin contributes to protective immunity in pneumonia-derived sepsis via fibrin polymerization and platelet-neutrophil interactions.Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro.A novel conditional platelet depletion mouse model reveals the importance of platelets in protection against Staphylococcus aureus bacteremia.Factor XIII Transglutaminase Supports the Resolution of Mucosal Damage in Experimental Colitis.Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling.Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif.Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection.Staphylococcus aureus Clumping Factor A Remains a Viable Vaccine Target for Prevention of S. aureus Infection.Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus DiseaseNew paradigms in sepsis: from prevention to protection of failing microcirculation.Platelets: essential components of the immune system.N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection.Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus.Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.Fibrinogen Is at the Interface of Host Defense and Pathogen Virulence in Staphylococcus aureus Infection.Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions.Innate immunity, hemostasis and matrix remodeling: PTX3 as a link.Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections.Cell Wall-Anchored Surface Proteins of Staphylococcus aureus: Many Proteins, Multiple Functions.Not fibrin(ogen), but fibrinogen or fibrinA coagulase-negative and non-haemolytic strain of Staphylococcus aureus for investigating the roles of SrtA in a murine model of bloodstream infection.Development of a Computational Model of Abscess Formation.
P2860
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P2860
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Genetic elimination of the bin ...... s host survival in septicemia.
@ast
Genetic elimination of the bin ...... s host survival in septicemia.
@en
type
label
Genetic elimination of the bin ...... s host survival in septicemia.
@ast
Genetic elimination of the bin ...... s host survival in septicemia.
@en
prefLabel
Genetic elimination of the bin ...... s host survival in septicemia.
@ast
Genetic elimination of the bin ...... s host survival in septicemia.
@en
P2093
P2860
P1433
P1476
Genetic elimination of the bin ...... s host survival in septicemia.
@en
P2093
Emanuel Smeds
Harini Raghu
Jay L Degen
Joni M Prasad
Joseph S Palumbo
Magnus Höök
Matthew J Flick
P2860
P304
P356
10.1182/BLOOD-2012-09-453894
P407
P577
2013-01-08T00:00:00Z