Protein-free efavirenz concentrations in cerebrospinal fluid and blood plasma are equivalent: applying the law of mass action to predict protein-free drug concentration.

Protein-free efavirenz concentrations in cerebrospinal fluid and blood plasma are equivalent: applying the law of mass action to predict protein-free drug concentration.

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http://www.wikidata.org/entity/Q36667153
Pharmacokinetic, Pharmacogenetic, and Other Factors Influencing CNS Penetration of AntiretroviralsEfavirenz and the CNS: what we already know and questions that need to be answeredIncreasing extracellular protein concentration reduces intracellular antiretroviral drug concentration and antiviral effect.Efavirenz Is Predicted To Accumulate in Brain Tissue: an In Silico, In Vitro, and In Vivo Investigation.Population Pharmacokinetic Modeling To Estimate the Contributions of Genetic and Nongenetic Factors to Efavirenz Disposition.Neuronal toxicity of efavirenz: a systematic review.Pharmacokinetics and pharmacodynamics of antiretrovirals in the central nervous system.HIV-associated Neurocognitive Disorders and Antiretroviral Therapy: Current Concepts and Controversies.Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines.Effect of blood protein concentrations on drug-dosing regimes: practical guidance.Central nervous system penetration of antiretroviral drugs: pharmacokinetic, pharmacodynamic and pharmacogenomic considerations.[Acute psychosis as a side effect of efavirenz therapy with metabolic anomalies: an important differential diagnosis of HIV-associated psychoses].Molecular mechanisms of serotonergic action of the HIV-1 antiretroviral efavirenz.Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.CNS penetration of ART in HIV-infected children.Development and validation of an LC-MS/MS assay for the quantification of efavirenz in different biological matrices.
P2860

Protein-free efavirenz concentrations in cerebrospinal fluid and blood plasma are equivalent: applying the law of mass action to predict protein-free drug concentration.

Item
http://www.wikidata.org/entity/Q36667153
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Protein-free efavirenz concent ...... otein-free drug concentration.
@ast
Protein-free efavirenz concent ...... otein-free drug concentration.
@en
type
label
Protein-free efavirenz concent ...... otein-free drug concentration.
@ast
Protein-free efavirenz concent ...... otein-free drug concentration.
@en
prefLabel
Protein-free efavirenz concent ...... otein-free drug concentration.
@ast
Protein-free efavirenz concent ...... otein-free drug concentration.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Protein-free efavirenz concent ...... otein-free drug concentration.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932