A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
about
DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancerNSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer CellsActivity of temozolomide in patients with advanced chemorefractory colorectal cancer and MGMT promoter methylation.Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib.Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties.O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer.Role of MGMT as biomarker in colorectal cancer.Synergistic activity of PARP inhibition by talazoparib (BMN 673) with temozolomide in pediatric cancer models in the pediatric preclinical testing program.Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer.A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells.Treatment of pituitary neoplasms with temozolomide: a review.Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.
P2860
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P2860
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@ast
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@en
type
label
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@ast
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@en
prefLabel
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@ast
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@en
P2093
P2860
P356
P1476
A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
@en
P2093
A J Watson
G P Margison
M R Middleton
N C Levitt
P Mortimer
P2860
P2888
P304
P356
10.1038/SJ.BJC.6604366
P407
P577
2008-05-13T00:00:00Z
P5875
P6179
1040655217