Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells.
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Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.Phase II trial of tipifarnib plus neoadjuvant doxorubicin-cyclophosphamide in patients with clinical stage IIB-IIIC breast cancer1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapysiRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model.High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886)The mitotic kinase Aurora--a promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα(+) breast cancer cells.Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells.Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.Enhancement of 5-fluorouracil-induced in vitro and in vivo radiosensitization with MEK inhibition.Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867Control of oncogenesis and cancer therapy resistance.Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen‑activated protein kinase kinase signaling pathwaysActivated estrogen receptor-mitogen-activated protein kinases cross talk confer acquired resistance to lapatinib.Modeling selective elimination of quiescent cancer cells from bone marrow.Use of APO2L/TRAIL with mTOR inhibitors in the treatment of glioblastoma multiforme.Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancerPIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancerApigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanismsTargeting prostate cancer based on signal transduction and cell cycle pathways.Mechanistic evaluation of the signaling events regulating curcumin-mediated chemosensitization of breast cancer cells to 5-fluorouracil.PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approachesDeletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cellsLoss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.Phase I-II study of the farnesyl transferase inhibitor tipifarnib plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in HER2/neu-negative inflammatory carcinoma and non-inflammatory estrogen receptor-positive breast carcinoma.Natural compounds to overcome cancer chemoresistance: toxicological and clinical issues.The Hippo pathway in chemotherapeutic drug resistance.Combination Therapy with AKT3 and PI3KCA siRNA Enhances the Antitumor Effect of Temozolomide and Carmustine in T98G Glioblastoma Multiforme Cells.Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer.Cytotoxic Effect of Coscinium fenestratum on Human Head and Neck Cancer Cell Line (HN31).Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.PTTG1 promotes migration and invasion of human non-small cell lung cancer cells and is modulated by miR-186.Increased radioresistance via G12S K-Ras by compensatory upregulation of MAPK and PI3K pathways in epithelial cancer.Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma.Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression.TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis.Rod-Shaped Active Drug Particles Enable Efficient and Safe Gene Delivery.Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells.Anticancer Effects of a Korean Herbal Medicine Formula (H9) via AMPK and HER2-PI3K/Akt Signaling in Breast Cancer Cells.Molecular mechanisms of hormone resistance of breast cancer.
P2860
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P2860
Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@ast
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@en
type
label
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@ast
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@en
prefLabel
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@ast
Roles of the PI-3K and MEK pat ...... stance in breast cancer cells.
@en
P2093
P2860
P356
P1476
Roles of the PI-3K and MEK pat ...... istance in breast cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6601048
P407
P50
P577
2003-07-01T00:00:00Z