Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome
about
Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseLow CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinomaDiscovering combinatorial interactions in survival dataClinical biomarkers for hypoxia targetingCarbonic anhydrase 9 is associated with chemosensitivity and prognosis in breast cancer patients treated with taxane and anthracycline.Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes.The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.Imaging hypoxia in gliomas.Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells.Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cellsTribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.Gene expression and hypoxia in breast cancer.Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification.Role of zinc in catalytic activity of carbonic anhydrase IX.Additive Influence of Extracellular pH, Oxygen Tension, and Pressure on Invasiveness and Survival of Human Osteosarcoma Cells.The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.Molecular aspects of tumour hypoxia.Tumour oxygenation: implications for breast cancer prognosis.Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases.Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.Overexpression of HIF1α and CAXI predicts poor outcome in early-stage triple negative breast cancer.Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms.Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells.Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.Expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer.Carbonic anhydrase IX expression is more predictive than prognostic in breast cancer.Paxillin and carbonic anhydrase IX are prognostic markers in gallbladder squamous cell/adenosquamous carcinomas and adenocarcinomas.Reply: Randomised studies with translational end points are required to further elucidate the prognostic and predictive value of CA IX.Association of chloride intracellular channel 4 and Indian hedgehog proteins with survival of patients with pancreatic ductal adenocarcinoma.Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma.Prognostic significance of carbonic anhydrase IX (CA-IX), endoglin (CD105) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) in breast cancer patients.HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome.UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system.2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer.Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma
P2860
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P2860
Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@ast
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@en
type
label
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@ast
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@en
prefLabel
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@ast
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@en
P2093
P2860
P356
P1476
Carbonic anhydrase-9 expressio ...... ciation with treatment outcome
@en
P2093
L V A M Beex
P2860
P2888
P304
P356
10.1038/SJ.BJC.6601122
P407
P577
2003-07-01T00:00:00Z