Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development
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WNT signaling in bone development and homeostasisDisruption of SUMO-specific protease 2 induces mitochondria mediated neurodegenerationWnt signaling in bone and muscleGpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis.Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation.Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors.Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescenceA Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density.Fibulin-5 deficiency causes developmental defect of premaxillary bone in miceStem cells of the suture mesenchyme in craniofacial bone development, repair and regeneration.Extraembryonic but not embryonic SUMO-specific protease 2 is required for heart development.Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.Distinct requirements of wls, wnt9a, wnt5b and gpc4 in regulating chondrocyte maturation and timing of endochondral ossification.Strong effect of SNP rs4988300 of the LRP5 gene on bone phenotype of Caucasian postmenopausal women.A Statistical Approach to Fine Mapping for the Identification of Potential Causal Variants Related to Bone Mineral Density.Wnt signaling and cellular metabolism in osteoblasts.Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.Wntless spatially regulates bone development through β-catenin-dependent and independent mechanisms.Rap1b Is an Effector of Axin2 Regulating Crosstalk of Signaling Pathways During Skeletal Development.
P2860
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P2860
Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
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2013年论文
@zh-cn
name
Gpr177, a novel locus for bone ...... enesis in skeletal development
@ast
Gpr177, a novel locus for bone ...... enesis in skeletal development
@en
type
label
Gpr177, a novel locus for bone ...... enesis in skeletal development
@ast
Gpr177, a novel locus for bone ...... enesis in skeletal development
@en
prefLabel
Gpr177, a novel locus for bone ...... enesis in skeletal development
@ast
Gpr177, a novel locus for bone ...... enesis in skeletal development
@en
P2860
P356
P1476
Gpr177, a novel locus for bone ...... enesis in skeletal development
@en
P2093
Ming Jiang
Takamitsu Maruyama
P2860
P304
P356
10.1002/JBMR.1830
P50
P577
2013-05-01T00:00:00Z