Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis
about
Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells.Caveolin-1 increases proinflammatory chemoattractants and blood-retinal barrier breakdown but decreases leukocyte recruitment in inflammation.A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherinA Highly Efficacious Herpes Simplex Virus 1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology via Humoral ImmunityEnhanced resistance of CXCR3 deficient mice to ocular HSV-1 infection is due to control of replication in the brain ependymaEvasion of early antiviral responses by herpes simplex viruses.Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS.Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis.RIG-I is required for VSV-induced cytokine production by murine glia and acts in combination with DAI to initiate responses to HSV-1.Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice.DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative diseaseHSV-1 targets lymphatic vessels in the eye and draining lymph node of mice leading to edema in the absence of a functional type I interferon response.Type I interferon and lymphangiogenesis in the HSV-1 infected cornea - are they beneficial to the host?Animal models of herpes simplex virus immunity and pathogenesis.Impact of Type I Interferon on the Safety and Immunogenicity of an Experimental Live-Attenuated Herpes Simplex Virus 1 Vaccine in Mice.Long-term consequences of topical dexamethasone treatment during acute corneal HSV-1 infection on the immune system.Defining nervous system susceptibility during acute and latent herpes simplex virus-1 infection.Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.Tumor Necrosis Factor Alpha-Induced Recruitment of Inflammatory Mononuclear Cells Leads to Inflammation and Altered Brain Development in Murine Cytomegalovirus-Infected Newborn Mice.Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.Herpesvirus-Associated Lymphadenitis Distorts Fibroblastic Reticular Cell Microarchitecture and Attenuates CD8 T Cell Responses to Neurotropic Infection in Mice Lacking the STING-IFNα/β Defense Pathways.The effect of captopril on the expression of MMP-9 and the prognosis of neurological function in herpes simplex encephalitis mice.Effects of Toll-like receptor 3 on herpes simplex virus type-1-infected mouse neural stem cells.New advances in CNS immunity against viral infection.DNA methylation of the TNF-α promoter region in peripheral blood monocytes and the cortex of human Alzheimer's disease patients.Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus.Insights into the pathogenesis of herpes simplex encephalitis from mouse models
P2860
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P2860
Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Microglia and a functional typ ...... e enlargement and encephalitis
@ast
Microglia and a functional typ ...... e enlargement and encephalitis
@en
type
label
Microglia and a functional typ ...... e enlargement and encephalitis
@ast
Microglia and a functional typ ...... e enlargement and encephalitis
@en
prefLabel
Microglia and a functional typ ...... e enlargement and encephalitis
@ast
Microglia and a functional typ ...... e enlargement and encephalitis
@en
P2093
P2860
P356
P1476
Microglia and a functional typ ...... e enlargement and encephalitis
@en
P2093
Anthony Alleman
Christopher D Conrady
Daniel J J Carr
Derek Royer
Douglas A Drevets
P2860
P304
P356
10.4049/JIMMUNOL.1203265
P407
P577
2013-02-04T00:00:00Z