Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription
about
Hijacked in cancer: the KMT2 (MLL) family of methyltransferasesCrystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domainAsh2l interacts with Tbx1 and is required during early embryogenesisFgfr3 is a transcriptional target of Ap2delta and Ash2l-containing histone methyltransferase complexes.CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.WRAD: enabler of the SET1-family of H3K4 methyltransferases.Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3).A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complexProtein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes.Mediator coordinates PIC assembly with recruitment of CHD1Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.The trithorax group protein Ash2l is essential for pluripotency and maintaining open chromatin in embryonic stem cells.An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior.Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.The many facets of MLL1 regulation.The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification.Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.
P2860
Q27006839-4A133A34-D107-466A-A58B-C6DEBAEE3BE5Q27666253-C35BF5E3-BAB3-48DE-91DD-FB93899063A4Q28586170-CB3E183C-A977-440F-855C-960504AC75C2Q33521703-B60C4AF7-0063-49D2-A1B4-9E589A6C0692Q33590983-045CCA01-CA26-4090-91DB-B75B2EBC58E4Q34278347-D8D4F669-E756-4203-A1EA-431A6033C4F3Q34467617-FEE5FE5C-2800-4C39-A255-8CA97B7E01F9Q34536856-35223898-22C9-49A8-BD17-04422DAA1E88Q34752160-BFADD7D6-081B-4FC9-BC68-92AA8E1177D9Q35494027-609372A1-1DD4-4915-B3C6-E7F1D073E57AQ35562908-6BBEE068-0B6E-4FD0-843D-07C538CD7BDDQ36620852-14CC9E82-0E28-4B57-AB57-B0BD89CBDE8EQ37048054-3D063911-30C5-4E36-919F-201FCB3C7867Q37410397-2D8CC703-82FB-477D-B11D-EF99F0B22C90Q38061869-26EEB72B-9663-4181-832B-AF79DE797B0EQ39000118-108DE7E1-84DD-44F3-B869-24CD6C904494Q51142663-0DEDB2ED-2195-4BEA-81D3-58CA6BE99D1AQ52369540-95DBF83F-B2E0-4CC7-9DC9-0CFB24AF3EE5
P2860
Transcription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcription
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@ast
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@en
type
label
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@ast
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@en
prefLabel
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@ast
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@en
P2093
P2860
P356
P1476
Transcription factor Ap2delta ...... o activate Hoxc8 transcription
@en
P2093
Cheryl C Tan
Hitomi Nishio
Jason Z Stoller
Jonathan A Epstein
K V Sindhu
Kimihiko Oishi
Martin J Walsh
Sahitya Puttreddy
Tamara J Lee
P2860
P304
P356
10.1073/PNAS.0711896105
P407
P577
2008-05-21T00:00:00Z