Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow.
about
Microfluidics and coagulation biologyVon Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kineticsTheory to predict shear stress on cells in turbulent blood flow.A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment.Platelets and cancer: a casual or causal relationship: revisited.Transport regulation of two-dimensional receptor-ligand associationMicrofluidic assessment of functional culture-derived platelets in human thrombi under flow.Microfluidic whole blood testing of platelet response to pharmacological agents.Multi-Constituent Simulation of Thrombus DepositionPotent Thrombolytic Effect of N-Acetylcysteine on Arterial Thrombi.Systems Analysis of Thrombus Formation.Acquired von Willebrand syndrome associated with left ventricular assist device.Fluid Mechanics of Blood Clot Formation.Role of fluid shear stress in regulating VWF structure, function and related blood disorders.Transport physics and biorheology in the setting of hemostasis and thrombosis.Utility of microfluidic devices to study the platelet-endothelium interface.Hemodynamic studies of platelet thrombosis using microfluidics.The potential role of platelets in the consensus molecular subtypes of colorectal cancer.Platelet "first responders" in wound response, cancer, and metastasis.Minimum wound size for clotting: flowing blood coagulates on a single collagen fiber presenting tissue factor and von Willebrand factor.Fibrin, γ'-fibrinogen, and transclot pressure gradient control hemostatic clot growth during human blood flow over a collagen/tissue factor wound.Pathological von Willebrand factor fibers resist tissue plasminogen activator and ADAMTS13 while promoting the contact pathway and shear-induced platelet activation.Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces.Prediction of Thrombus Growth: Effect of Stenosis and Reynolds Number.Space and Time Resolved Detection of Platelet Activation and von Willebrand Factor Conformational Changes in Deep Suspensions.Hemodynamic force triggers rapid NETosis within sterile thrombotic occlusions.The type 2B p.R1306W natural mutation of von Willebrand factor dramatically enhances the multimer sensitivity to shear stress.Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation.14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding.
P2860
Q27026691-C5D4D8B0-E1A7-48E6-A679-8CD918DBF62FQ27303207-85B98998-38FF-4A9A-BFE3-B43EF096B2D5Q34109972-C8E5501C-1427-4F36-8984-164761ADFB31Q34170393-EE78ACBE-A5AC-431B-B9D6-EDEE2A6FA3CFQ34294719-A389B3F4-AA70-4909-9448-FC73208DF49BQ35333646-7E0D387D-79C8-4ADB-BB5C-4461EE45A20DQ36119331-E14C3400-81CD-4DF1-8A72-B2FE8E0EC307Q36253661-1CB2CEE6-A876-4980-9D27-8DA04D10BCA2Q36285316-618D4695-78B2-4055-8939-70D2811B33D0Q36367419-D74797E3-EF8A-470E-AE40-A35D7952C6AFQ36855652-D247525B-A7C2-46DB-8F0E-3C2013436C2DQ37035825-5E261883-9E17-463E-8774-4BF5988978F1Q38559498-9BFF2256-92D3-4E3B-9B6A-8CE33F07FEA1Q38645643-14B53026-CFA7-4CBF-BBC4-EBB612A0A601Q38723930-C6371E61-719A-4FB5-92E8-DE73EDBBA920Q39208821-18CBB8C4-CFF1-4818-993D-780391CAAEB5Q39359352-EBDACAD2-7368-44A5-B507-110A64807B61Q39417307-111A70AA-4637-4864-A0D9-11E597000CD5Q39449769-2CC05DB7-D52F-4A23-BC79-77FB78487162Q42365902-888A2212-7043-44DB-847B-A27561695DA4Q42557135-2B17A716-917E-45E9-9B79-94A986A80660Q42581851-20C3F8A1-58D8-419F-9C32-772FC644A296Q42725749-B65BCC5C-E86D-4306-8BC0-6BE96037DD73Q45058323-09B87EEC-A56D-4F48-946E-A8EB1BE976EBQ46866160-11DD6B00-C4B9-472C-89CC-A44F6F65A2B6Q47331601-ECDDCDEA-CAEB-4530-B182-1C07E66DE811Q50863278-BB8B5336-3670-4C78-A7C5-A72391CD7CB0Q50974811-8F2ACFC9-C7A6-4D56-9EC8-FC775CFC57EEQ52330622-43824FF3-5C90-46C3-9151-974AA4075E36Q55153557-5790DDFD-2E3A-431C-AC63-0D2B931D0499
P2860
Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Direct observation of von Will ...... exposure to pathological flow.
@ast
Direct observation of von Will ...... exposure to pathological flow.
@en
type
label
Direct observation of von Will ...... exposure to pathological flow.
@ast
Direct observation of von Will ...... exposure to pathological flow.
@en
prefLabel
Direct observation of von Will ...... exposure to pathological flow.
@ast
Direct observation of von Will ...... exposure to pathological flow.
@en
P2860
P1476
Direct observation of von Will ...... exposure to pathological flow.
@en
P2093
Scott L Diamond
Thomas V Colace
P2860
P304
P356
10.1161/ATVBAHA.112.300522
P407
P577
2012-10-25T00:00:00Z