Omalizumab reverses the phenotypic and functional effects of IgE-enhanced Fc epsilonRI on human skin mast cells.
about
Relationships between levels of serum IgE, cell-bound IgE, and IgE-receptors on peripheral blood cells in a pediatric population.IgE, mast cells, basophils, and eosinophils.Omalizumab therapy in three patients with chronic autoimmune urticaria.Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation.In vitro desensitization of human skin mast cells.New concepts in chronic urticaria.CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells.Atopic dermatitis - from new pathophysiologic insights to individualized therapy.Use of omalizumab in the treatment of food allergy and anaphylaxis.Developing therapies for peanut allergy.Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria.Structure of the omalizumab Fab.A Role for Human Skin Mast Cells in Dengue Virus Infection and Systemic Spread.Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells.Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction.Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens.
P2860
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P2860
Omalizumab reverses the phenotypic and functional effects of IgE-enhanced Fc epsilonRI on human skin mast cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@ast
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@en
type
label
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@ast
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@en
prefLabel
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@ast
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@en
P2093
P2860
P1476
Omalizumab reverses the phenot ...... onRI on human skin mast cells.
@en
P2093
Gregorio Gomez
Lawrence B Schwartz
Mika Shima
Sherryline Jogie-Brahim
P2860
P304
P356
10.4049/JIMMUNOL.179.2.1353
P407
P577
2007-07-01T00:00:00Z