An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
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Drosophila as a Potential Model for Ocular TumorsThe interplay between obesity and cancer: a fly viewAn inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell linesInsulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing.Dihydroisoxazole inhibitors of Anopheles gambiae seminal transglutaminase AgTG3RNAi screening in Drosophila cells and in vivo.Anti-cancer drug discovery: update and comparisons in yeast, Drosophila, and zebrafish.Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis.Drosophila Cancer Models Identify Functional Differences between Ret Fusions.EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.Metabolic regulation via enzyme filamentationThe Lantibiotic NAI-107 Efficiently Rescues Drosophila melanogaster from Infection with Methicillin-Resistant Staphylococcus aureus USA300.Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila.Oncogenic mutations produce similar phenotypes in Drosophila tissues of diverse origins.Fruit flies as a powerful model to drive or validate pain genomics efforts.An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignant brain tumour growthNatural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and Invasion.Opportunities to Apply the 3Rs in Safety Assessment Programs.A novel hanging spherical drop system for the generation of cellular spheroids and high throughput combinatorial drug screening.Simple animal models for amyotrophic lateral sclerosis drug discovery.Critical roles of CTP synthase N-terminal in cytoophidium assemblyThe translational relevance of Drosophila in drug discovery.Hippo signaling promotes JNK-dependent cell migration.Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo.A fruit fly in the nanoworld: once again Drosophila contributes to environment and human health.Reverse-engineering organogenesis through feedback loops between model systems.MAPK pathway inhibitors rescue lethal phenotypes in a BRAF gain-of-function Drosophila melanogaster model.Non-mammalian models of multiple endocrine neoplasia type 2.A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant.Myc suppresses tumor invasion and cell migration by inhibiting JNK signaling.Modelling Cooperative Tumorigenesis in Drosophila.Why mammalian wound-healing researchers may wish to turn to Drosophila as a model.Studying tumor growth in Drosophila using the tissue allograft method.
P2860
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P2860
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@ast
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@en
type
label
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@ast
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@en
prefLabel
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@ast
An in vivo large-scale chemica ...... or anti-cancer drug discovery.
@en
P2093
P2860
P50
P356
P1476
An in vivo large-scale chemica ...... for anti-cancer drug discovery
@en
P2093
Anthony M Brumby
Ian P Street
John P Parisot
Lee F Willoughby
Tanja Schlosser
P2860
P304
P356
10.1242/DMM.009985
P577
2012-09-20T00:00:00Z