Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant.
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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epitheliaThymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice ModelsNo requirement for V(D)J recombination in p53-deficient thymic lymphomaExpression of a gonadotropin-releasing hormone receptor-simian virus 40 T-antigen transgene has sex-specific effects on the reproductive axis.Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53.Association between SV40 and non-Hodgkin's lymphoma.Transforming functions of Simian Virus 40.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisRegulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice.A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small-t antigen and is required for transformation in small-t antigen-dependent assays.A simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.Enterocyte proliferation and intestinal hyperplasia induced by simian virus 40 T antigen require a functional J domainAssociation of p300 and CBP with simian virus 40 large T antigenThe amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigenSimian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptorT antigen transgenic mouse modelsPolyomavirus T antigens: molecular chaperones for multiprotein complexes.Simian virus 40 large T antigen J domain and Rb-binding motif are sufficient to block apoptosis induced by growth factor withdrawal in a neural stem cell line.The inhibition of cultured myoblast differentiation by the simian virus 40 large T antigen occurs after myogenin expression and Rb up-regulation and is not exerted by transformation-competent cytoplasmic mutants.Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain.The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen.Different functions are required for initiation and maintenance of immortalization of rat embryo fibroblasts by SV40 large T antigen.T antigens encoded by replication-defective simian virus 40 mutants dl1135 and 5080.Cell and molecular biology of simian virus 40: implications for human infections and disease.Simian virus 40 T antigen-induced amplification of pre-parietal cells in transgenic mice. Effects on other gastric epithelial cell lineages and evidence for a p53-independent apoptotic mechanism that operates in a committed progenitor.Ependymal and choroidal cells in culture: characterization and functional differentiation.
P2860
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P2860
Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@ast
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@en
type
label
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@ast
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@en
prefLabel
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@ast
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@en
P2093
P2860
P356
P1476
Use of transgenic mice reveals ...... antigen amino-terminal mutant.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.6.3255
P407
P577
1993-06-01T00:00:00Z