The K-fgf/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathway
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Fibroblast growth factor 3 is tumorigenic for mouse mammary cells orthotopically implanted in nude miceA new approach to the molecular basis of neoplastic transformation in the brain.The N-terminal propiece of interleukin 1 alpha is a transforming nuclear oncoproteinCell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors.A retrovirus carrying the K-fgf oncogene induces diffuse meningeal tumors and soft-tissue fibrosarcomas.Release of basic fibroblast growth factor, an angiogenic factor devoid of secretory signal sequence: a trivial phenomenon or a novel secretion mechanism?Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription.A zinc finger gene from Onchocerca volvulus encodes a protein with a functional signal peptide and an unusual Ser-His finger motif.The Int-2/Fgf-3 oncogene product is secreted and associates with extracellular matrix: implications for cell transformation.Paracrine and autocrine effects of fibroblast growth factor-4 in endothelial cells.Tumoral progression of human breast epithelial cells secreting FGF2 and FGF4.Fibroblast growth factor receptors 1 and 2 are differentially regulated in murine embryonal carcinoma cells and in response to fibroblast growth factor-4.Inositolhexakisphosphate (InsP6): an antagonist of fibroblast growth factor receptor binding and activity.Retention of fibroblast growth factor 3 in the Golgi complex may regulate its export from cells.Acidic FGF and EGF are involved in the autocrine growth stimulation of a human nasopharyngeal carcinoma cell line and sub-line cells.Cell transformation by kFGF requires secretion but not glycosylation.Cleavage of K-FGF produces a truncated molecule with increased biological activity and receptor binding affinity.Notch activation suppresses fibroblast growth factor-dependent cellular transformation.Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex.Transformation of rabbit vascular smooth muscle cells by human cytomegalovirus morphological transforming region I
P2860
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P2860
The K-fgf/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathway
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@ast
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@en
type
label
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@ast
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@en
prefLabel
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@ast
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@en
P2860
P356
P1476
The K-fgf/hst oncogene induces ...... ation of the mitogenic pathway
@en
P2093
C Basilico
D Talarico
P2860
P304
P356
10.1128/MCB.11.2.1138
P407
P577
1991-02-01T00:00:00Z