Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex.
about
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoformsMultiple variable first exons: a mechanism for cell- and tissue-specific gene regulationGlucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liverCloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversityRegulation of the rat UGT1A6 by glucocorticoids involves a cryptic glucocorticoid response elementIdentification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiolXenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complexAdaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymesFunctions and transcriptional regulation of PAH-inducible human UDP-glucuronosyltransferases.Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase.Coordinate regulation of drug metabolism by xenobiotic nuclear receptors: UGTs acting together with CYPs and glucuronide transporters.Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen.Takashi Iyanagi: UGT1 gene complex: from Gunn rat to human.Disruption of thyroid hormone homeostasis in Ugt1a-deficient Gunn rats by microsomal enzyme inducers is not due to enhanced thyroxine glucuronidation.Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species.Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear faA critical amino acid residue, asp446, in UDP-glucuronosyltransferase.Opposite regulation of bilirubin and 4-nitrophenol UDP-glucuronosyltransferase mRNA levels by 3,3',5 triiodo-L-thyronine in rat liver.Change in the gene expression of hepatic tamoxifen-metabolizing enzymes during the process of tamoxifen-induced hepatocarcinogenesis in female rats.Transcriptional activation of the UDP-glucuronosyltransferase 1A7 gene in rat liver by aryl hydrocarbon receptor ligands and oltipraz.Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo.The novel UGT1 gene complex links bilirubin, xenobiotics, and therapeutic drug metabolism by encoding UDP-glucuronosyltransferase isozymes with a common carboxyl terminus.Expression of UGT1A subfamily in rat brain.
P2860
Q24301940-7A163CD1-856B-4FED-BE91-255C1A24F1C3Q24629923-159F6A70-E7AF-44DC-A7A0-84C1A8060B62Q28343335-200A9E60-8C2A-4CB1-9308-100416176DEBQ28472840-97EB1816-8729-48B0-BA8E-9C0647AD484EQ28570810-5AD77DC0-AA4A-4B65-AE3E-1704725BCCD9Q28579604-1245F923-4CB0-4DF6-AE26-11BAEA662DEDQ28581823-2BCB95D8-C047-4793-B3EC-0AF74C8D88B4Q33283468-0664ED7A-D6D4-4746-B7F1-BCA3EF54F1CCQ33639755-C28FBA38-4BA5-436B-9DCC-AEE7A62F4629Q34787034-C3C7EE1F-C73E-4D87-A3FF-855A282B6968Q35956173-3E25EED0-69E5-402D-A56C-2E46BFAEAC25Q37221922-1ACABBA4-B92E-4EE6-8B92-6164E6379B1FQ37618795-BD9EF2A6-C10B-4E08-885D-96FB9DFFBCCFQ38692449-F8878A22-6249-49D8-9A8D-F0A119EA7794Q38695374-06BD8138-7BEE-45A0-90DC-1C9BB36B990AQ40539522-A0230FAC-C5D5-4854-AB2D-F36DE5162D58Q42133496-2F9FEBF7-E6B2-47D5-88F1-A29444368D37Q42159680-9057A799-D7B3-4526-BCCD-5824096916A6Q42556379-5DF7F1F9-BF48-45E5-AD80-173C3EB298EFQ43918589-4FB2A28F-02C9-47B4-8E8A-121770EE9CA3Q45109965-E3A6E993-0A42-4E5A-BB0F-C7AE2371F14AQ45885418-051202F6-7785-42C9-86B3-808EE860294BQ48059211-6E79ABC7-9DBC-42C2-875E-0753BA940BE0Q51380562-1DBA034C-B89A-404F-88F3-AB24CC097C84
P2860
Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@ast
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@en
type
label
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@ast
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@en
prefLabel
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@ast
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@en
P2093
P356
P1476
Drug-responsive and tissue-spe ...... family 1 (UGT1) gene complex.
@en
P2093
P304
P356
10.1093/JB/117.2.392
P577
1995-02-01T00:00:00Z