Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells.
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Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiriGrowth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifsHerpesvirus saimiri.Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb.Downregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural hostLck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene products.A herpesvirus saimiri protein required for interleukin-2 independence is associated with membranes of transformed T cells.Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus SaimiriLimited heterogeneity of T cell receptor BV usage in aplastic anemia.The superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells.Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells.Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.Endogenous production of beta-chemokines by CD4+, but not CD8+, T-cell clones correlates with the clinical state of human immunodeficiency virus type 1 (HIV-1)-infected individuals and may be responsible for blocking infection with non-syncytium-indHerpesvirus saimiri transforms human T-cell clones to stable growth without inducing resistance to apoptosis.Immortalization of human T cells expressing T-cell receptor gamma delta by herpesvirus saimiri.Herpesvirus saimiri immortalization of Aotus T lymphocytes specific for an immunogenically modified peptide of Plasmodium falciparum merozoite surface antigen 2.Efficient lentiviral transduction of Herpesvirus saimiri immortalized T cells as a model for gene therapy in primary immunodeficiencies.Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation.A novel CD18 genomic deletion in a patient with severe leucocyte adhesion deficiency: a possible CD2/lymphocyte function-associated antigen-1 functional association in humans.Localization of soluble major histocompatibility class II-peptide complexes on T cell surface.A human T-cell leukemia virus Tax variant incapable of activating NF-kappaB retains its immortalizing potential for primary T-lymphocytes.Antigen-specific apoptosis in immortalized T cells by soluble MHC class II-peptide complexes.Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells.Refolding and reconstitution of functionally active complexes of human leukocyte antigen DR2 and myelin basic protein peptide from recombinant alpha and beta polypeptide chains.Functional long-term thymidine kinase suicide gene expression in human T cells using a herpesvirus saimiri vector.NF-kappaB activation by the viral oncoprotein StpC enhances IFN-gamma production in T cells.Functionally active recombinant alpha and beta chain-peptide complexes of human major histocompatibility class II molecules.
P2860
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P2860
Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Transformation of human T-cell ...... asic protein-specific T cells.
@ast
Transformation of human T-cell ...... asic protein-specific T cells.
@en
type
label
Transformation of human T-cell ...... asic protein-specific T cells.
@ast
Transformation of human T-cell ...... asic protein-specific T cells.
@en
prefLabel
Transformation of human T-cell ...... asic protein-specific T cells.
@ast
Transformation of human T-cell ...... asic protein-specific T cells.
@en
P2093
P2860
P356
P1476
Transformation of human T-cell ...... asic protein-specific T cells.
@en
P2093
Czlonkowska A
Fickenscher H
Fleckenstein B
Hohlfeld R
Müller-Fleckenstein I
P2860
P304
11049-11053
P356
10.1073/PNAS.90.23.11049
P407
P577
1993-12-01T00:00:00Z