Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
about
Shepherding AKT and androgen receptor by Ack1 tyrosine kinaseExome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaTransposon-based screens for cancer gene discovery in mouse modelsRole of Ikaros in T-cell acute lymphoblastic leukemiaTumorigenicity of the miR-17-92 cluster distilledIn vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progressionApplications of DNA integrating elements: Facing the bias bullyHow animal models of leukaemias have already benefited patientsThe PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and LeukemiaJdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygositymir-17-92, a cluster of miRNAs in the midst of the cancer networkThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionDosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 functionRepression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathwayGenetic screens using the piggyBac transposonEffect of Xpcl1 activation and p27(Kip1) loss on gene expression in murine lymphomaRREB1 transcription factor splice variants in urologic cancer.Extracting consistent knowledge from highly inconsistent cancer gene data sources.Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer.Mouse models of cancer as biological filters for complex genomic data.Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.Gene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes.Making sense of cancer genomic data.Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypesModeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approachPredicting genetic modifier loci using functional gene networksNovel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.Sirt3, mitochondrial ROS, ageing, and carcinogenesis.PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.An Integrated Genetic-Genomic Approach for the Identification of Novel Cancer Loci in Mice Sensitized to c-Myc-Induced Apoptosis.Insertional hypermutation in mineral oil-induced plasmacytomasSIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis.Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.Cancer gene discovery in mouse and man.BayMiR: inferring evidence for endogenous miRNA-induced gene repression from mRNA expression profiles.GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis.Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.
P2860
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P2860
Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Large-scale mutagenesis in p19 ...... their collaborative networks.
@ast
Large-scale mutagenesis in p19 ...... their collaborative networks.
@en
type
label
Large-scale mutagenesis in p19 ...... their collaborative networks.
@ast
Large-scale mutagenesis in p19 ...... their collaborative networks.
@en
prefLabel
Large-scale mutagenesis in p19 ...... their collaborative networks.
@ast
Large-scale mutagenesis in p19 ...... their collaborative networks.
@en
P2093
P2860
P50
P1433
P1476
Large-scale mutagenesis in p19 ...... their collaborative networks.
@en
P2093
Anthony G Uren
Anton Berns
David J Adams
Ellen Tanger
Jane Rogers
Jenny Mattison
Jos Jonkers
Konstantin Matentzoglu
Lodewyk Wessels
P2860
P304
P356
10.1016/J.CELL.2008.03.021
P407
P577
2008-05-01T00:00:00Z