Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine
about
Beneficial and detrimental role of adenosine signaling in diseases and therapyAdenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.Molecular pathogenesis of skin fibrosis: insight from animal models.Adenosine signaling during acute and chronic disease statesGenetic deletion of the adenosine A2A receptor confers postnatal development of relative myopia in mice.Adenosine in fibrosis.Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiencyPharmacological blockade of adenosine A2A receptors diminishes scarringAdenosine A2A receptor plays an important role in radiation-induced dermal injuryExtracellular adenosine levels are associated with the progression and exacerbation of pulmonary fibrosis.Adenosine receptor agonists for promotion of dermal wound healing.Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanismAdenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balanceAdenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.The adenosinergic immunomodulatory drugs.Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth.Noncanonical transforming growth factor beta signaling in scleroderma fibrosisNucleotides and nucleoside signaling in the regulation of the epithelium to mesenchymal transition (EMT).Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.Design and application of locally delivered agonists of the adenosine A(2A) receptor.Aberrant immune response with consequent vascular and connective tissue remodeling - causal to scleroderma and associated syndromes such as Raynaud phenomenon and other fibrosing syndromes?Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases.New role of the human equilibrative nucleoside transporter 1 (hENT1) in epithelial-to-mesenchymal transition in renal tubular cells.Signaling pathways involving adenosine A2A and A2B receptors in wound healing and fibrosis.Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.Adenosine mediates transforming growth factor-beta 1 release in kidney glomeruli of diabetic rats.Hepatoprotective Effect of Low Doses of Caffeine on CCl4-Induced Liver Damage in Rats.Adenosine A2a Receptor Blockade Diminishes Wnt/β-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis.
P2860
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P2860
Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@ast
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@en
type
label
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@ast
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@en
prefLabel
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@ast
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@en
P2093
P2860
P50
P1476
Pharmacological blockade of A2 ...... l of elevated tissue adenosine
@en
P2093
Edwin S L Chan
Patricia Fernández
Sean Trzaska
Tuere Wilder
P2860
P304
P356
10.2353/AJPATH.2008.070952
P407
P577
2008-05-08T00:00:00Z