Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice - Wikidata - awgldk - TriplyDB

Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice

Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice

http://www.wikidata.org/entity/Q36691235

about

Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit Role of Myosin Va in the plasticity of the vertebrate neuromuscular junction in vivo Novel functional epsilon-subunit polypeptide generated by a single nucleotide deletion in acetylcholine receptor deficiency congenital myasthenic syndrome Congenital myasthenic syndromes due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutations AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane.Degeneration of neuromuscular junction in age and dystrophy.Spontaneous muscle action potentials fail to develop without fetal-type acetylcholine receptors.Differences in pharmacodynamic responses to rocuronium in normal or injured orbicularis oris are associated with expression of acetylcholine receptor subunits Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms.Time lapse in vivo visualization of developmental stabilization of synaptic receptors at neuromuscular junctions Early postnatal death and motor disorders in mice congenitally deficient in calnexin expression.Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors.Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin Targeting of the ETS factor GABPalpha disrupts neuromuscular junction synaptic function.Structural correlates of affinity in fetal versus adult endplate nicotinic receptors Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.Defective Acetylcholine Receptor Subunit Switch Precedes Atrophy of Slow-Twitch Skeletal Muscle Fibers Lacking ERK1/2 Kinases in Soleus Muscle.Stem cell-derived neurotrophic support for the neuromuscular junction in spinal muscular atrophy.Novel role for cyclin-dependent kinase 2 in neuregulin-induced acetylcholine receptor epsilon subunit expression in differentiated myotubes.Acetylcholine receptor channel subtype directs the innervation pattern of skeletal muscle.Disparate dysfunction of skeletal muscles located near and distant from burn site in the rat.Slow myosin heavy chain expression in the absence of muscle activity.Changes in acetylcholine receptor function induce shifts in muscle fiber type composition.Myasthenic syndromes in Turkish kinships due to mutations in the acetylcholine receptor.Congenital myasthenic syndrome caused by novel loss-of-function mutations in the human AChR epsilon subunit gene.Congenital myasthenic syndromes. New insights from molecular genetic and patch-clamp studies.Neuromuscular junctions (NMJs): ultrastructural analysis and nicotinic acetylcholine receptor (nAChR) subunit mRNA expression in offspring subjected to protein restriction throughout pregnancy.MuSK: a new target for lethal fetal akinesia deformation sequence (FADS).Different functions of fetal and adult AChR subtypes for the formation and maintenance of neuromuscular synapses revealed in epsilon-subunit-deficient mice.Animal Models of the Neuromuscular Junction, Vitally Informative for Understanding Function and the Molecular Mechanisms of Congenital Myasthenic Syndromes.Whole Exome Sequencing Is the Preferred Strategy to Identify the Genetic Defect in Patients With a Probable or Possible Mitochondrial Cause

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P2860

Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice

http://www.wikidata.org/entity/Q36691235

description

1996 nî lūn-bûn

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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1996年论文

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1996年论文

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Acetylcholine receptor epsilon ...... phy in juvenile and adult mice

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Proceedings of the National Academy of Sciences of the United States of America

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Acetylcholine receptor epsilon ...... phy in juvenile and adult mice

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A Villarroel

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A Wernig

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B Sakmann

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C Berberich

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H R Brenner

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H Schwarz

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M Koenen

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V Witzemann

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P2860

Single-channel currents recorded from membrane of denervated frog muscle fibres

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Voltage clamp analysis of acetylcholine produced end-plate current fluctuations at frog neuromuscular junction

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate.

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor.

Local neurotrophic repression of gene transcripts encoding fetal AChRs at rat neuromuscular synapses.

Neural factors regulate AChR subunit mRNAs at rat neuromuscular synapses.

Maturation of transmission in reinnervated mouse soleus muscle.

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