KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia
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Ion Channels in the HeartEmerging directions in the genetics of atrial fibrillationInward rectifiers and their regulation by endogenous polyaminesAtrial arrhythmias in inherited arrhythmogenic disordersIon channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac deathMathematical approaches to understanding and imaging atrial fibrillation: significance for mechanisms and managementShort QT syndrome in pediatrics.Attraction of rotors to the pulmonary veins in paroxysmal atrial fibrillation: a modeling study.Beyond the Electrocardiogram: Mutations in Cardiac Ion Channel Genes Underlie Nonarrhythmic Phenotypes.Short QT and atrial fibrillation: A KCNQ1 mutation-specific disease. Late follow-up in three unrelated children.Improved understanding of the pathophysiology of atrial fibrillation through the lens of discrete pathological pathwaysAtrial Fibrillation and SCN5A Variants.Neuroanatomical correlates of atrial fibrillation: a longitudinal MRI study.Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1.Rapid and MR-Independent IK1 Activation by Aldosterone during Ischemia-Reperfusion.Your Father and Grandfather's Atrial Fibrillation: A Review of the Genetics of the Most Common Pathologic Cardiac DysrhythmiaComputational modeling of cardiac optogenetics: Methodology overview & review of findings from simulationsAtrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria.Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.The Major Role of IK1 in Mechanisms of Rotor Drift in the Atria: A Computational Study.Atrial fibrillation: mechanisms, therapeutics, and future directions.Mutations specific to the Rac-GEF domain of TRIO cause intellectual disability and microcephaly.Novel insight into the natural history of short QT syndrome.Atrial selectivity of antiarrhythmic drugs.Advances in modeling ventricular arrhythmias: from mechanisms to the clinic.The usual suspects in sudden cardiac death of the young: a focus on inherited arrhythmogenic diseases.Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel.Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia.Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Styrax blocks inward and outward current of Kir2.1 channel.PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression.Chloride Channels are Involved in the Development of Atrial Fibrillation - A Transcriptomic and proteomic Study.Computational analysis of the electromechanical consequences of short QT syndrome.Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts.In silico investigation of the short QT syndrome, using human ventricle models incorporating electromechanical coupling.Slow [Na+]i dynamics impacts arrhythmogenesis and spiral wave reentry in cardiac myocyte ionic model.Partial IK1 blockade destabilizes spiral wave rotation center without inducing wave breakup and facilitates termination of reentrant arrhythmias in ventricles.
P2860
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P2860
KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@ast
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@en
type
label
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@ast
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@en
prefLabel
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@ast
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@en
P2093
P2860
P50
P356
P1476
KCNJ2 mutation in short QT syn ...... and ventricular proarrhythmia
@en
P2093
Andrew Blaufox
Kushal Shah
Makarand Deo
Omer Berenfeld
Sami F Noujaim
Sandeep V Pandit
Yanfei Ruan
P2860
P304
P356
10.1073/PNAS.1218154110
P407
P577
2013-02-25T00:00:00Z