The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.
about
Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model.Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10The solution structure of [d(CGC)r(aaa)d(TTTGCG)](2): hybrid junctions flanked by DNA duplexesMultispectroscopic studies on the interaction of a copper(ii) complex of ibuprofen drug with calf thymus DNA.Targeting the HIV trans-activation responsive region--approaches towards RNA-binding drugs.Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism.Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization ReactionReducing levels of toxic RNA with small moleculesOxidative base damage in RNA detected by reverse transcriptaseAutomated synthesis of oligosaccharides as a basis for drug discovery.The solution structure of a 3'-phenazinium (Pzn) tethered DNA-RNA duplex with a dangling adenosine: r(5'G-AUUGAA3'):d(5'TCAATC3'-Pzn)The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroismBinding of Hoechst 33258 to the TAR RNA of HIV-1. Recognition of a pyrimidine bulge-dependent structure.Binding, electrochemical activation, and cleavage of DNA by cobalt(II) tetrakis-N-methylpyridyl porphyrin and its beta-pyrrole brominated derivativeBinding to the DNA minor groove by heterocyclic dications: from AT-specific monomers to GC recognition with dimers.Effect of LNA modifications on small molecule binding to nucleic acids.The affinity of an oligodeoxynucleotide-peptide conjugate for an RNA hairpin loop depends on stereochemistry at the DNA-peptide junction.Palladium(II) Complexes of Biorelevant Ligands. Synthesis, Structures, Cytotoxicity and Rich DNA/HSA Interaction Studies.Anti-Pneumocystis carinii pneumonia activity of dicationic 2,4-diarylpyrimidines.Spectroscopic and molecular modeling based approaches to study on the binding behavior of DNA with a copper (II) complex.An investigation on new ruthenium(II) hydrazone complexes as anticancer agents and their interaction with biomolecules.Imidazolyl-Naphthalenediimide-Based Threading Intercalators of DNA.Synthesis and characterization of the ligand based on benzimidazole and its copper complex: DNA binding and antioxidant activity.The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse transcription.Synthetic RNA recognition motifs that selectively recognize HIV-1 trans-activation response element hairpin RNA.Synthesis of dicationic diarylpyridines as nucleic-acid binding agents.Synthesis and properties of 4'-ThioDNA: unexpected RNA-like behavior of 4'-ThioDNA.Identification and characterization of an endo/exonuclease in Pneumocystis carinii that is inhibited by dicationic diarylfurans with efficacy against Pneumocystis pneumonia.Synthesis of dicationic diaryltriazines nucleic acid binding agents.Inhibitory properties of nucleic acid-binding ligands on protein synthesis.Synthesis and characterization of polyamine-based biomimetic catalysts as artificial ribonuclease.The size of the aryl linker between two polyaza-cyclophane moieties controls the binding selectivity to ds-RNA vs. ds-DNA.2,4-Diamino-6,7-dimethylpteridine as a fluorescent ligand for binding and sensing an orphan cytosine in RNA duplexes.Aminoglycoside-quinacridine conjugates: towards recognition of the P6.1 element of telomerase RNA.Novel DNA/RNA-targeting amino acid beacon for the versatile incorporation at any position within the peptide backbone.Selectivity of a thiosemicarbazonatocopper(ii) complex towards duplex RNA. Relevant noncovalent interactions both in solid state and solution.Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.Loading of an anti-cancer drug onto graphene oxide and subsequent release to DNA/RNA: a direct optical detection.Pyridine and p-Nitrophenyl Oxime Esters with Possible Photochemotherapeutic Activity: Synthesis, DNA Photocleavage and DNA Binding Studies.Acetyl pyridine-based palladium(II) compounds as an artificial metallonucleases.
P2860
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P2860
The search for structure-specific nucleic acid-interactive drugs: effects of compound structure on RNA versus DNA interaction strength.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The search for structure-speci ...... rsus DNA interaction strength.
@ast
The search for structure-speci ...... rsus DNA interaction strength.
@en
type
label
The search for structure-speci ...... rsus DNA interaction strength.
@ast
The search for structure-speci ...... rsus DNA interaction strength.
@en
prefLabel
The search for structure-speci ...... rsus DNA interaction strength.
@ast
The search for structure-speci ...... rsus DNA interaction strength.
@en
P2093
P356
P1433
P1476
The search for structure-speci ...... rsus DNA interaction strength.
@en
P2093
P304
P356
10.1021/BI00066A035
P407
P577
1993-04-01T00:00:00Z