Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. - Wikidata - awgldk - TriplyDB

Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.

Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.

http://www.wikidata.org/entity/Q36700240

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Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity pH Dependent but not P-gp Dependent Bidirectional Transport Study of S-propranolol: The Importance of Passive Diffusion Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT Recent advances in understanding proton coupled peptide transport via the POT family The altered renal and hepatic expression of solute carrier transporters (SLCs) in type 1 diabetic mice Genetic mechanisms of bone digestion and nutrient absorption in the bone-eating worm Osedax japonicus inferred from transcriptome and gene expression analyses The Concise Guide to PHARMACOLOGY 2013/14: transporters.Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.Amino acid homeostasis and signalling in mammalian cells and organisms.Expression and regulation of the proton-coupled oligopeptide transporter PhT2 by LPS in macrophages and mouse spleen.Computing Substrate Selectivity in a Peptide Transporter.Divergent developmental expression and function of the proton-coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and rat Development and characterization of a novel mouse line humanized for the intestinal peptide transporter PEPT1 Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells.Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: whole-genome analysis in patients with hepatocellular carcinoma.Structure determination of a major facilitator peptide transporter: Inward facing PepTSt from Streptococcus thermophilus crystallized in space group P3121.Mathematical modeling of acid-base physiology.Human oligopeptide transporter 2 (PEPT2) mediates cellular uptake of polymyxins.Significance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice.Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil The proton-coupled oligopeptide transporter 1 plays a major role in the intestinal permeability and absorption of 5-aminolevulinic acid Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice Functional and molecular expression of the proton-coupled oligopeptide transporters in spleen and macrophages from mouse and human Population pharmacokinetic modeling of cefadroxil renal transport in wild-type and Pept2 knockout mice Impact of peptide transporter 1 on the intestinal absorption and pharmacokinetics of valacyclovir after oral dose escalation in wild-type and PepT1 knockout mice.Impact of intestinal PepT1 on the kinetics and dynamics of N-formyl-methionyl-leucyl-phenylalanine, a bacterially-produced chemotactic peptide.In vivo absorption and disposition of cefadroxil after escalating oral doses in wild-type and PepT1 knockout mice.Emerging transporters of clinical importance: an update from the International Transporter Consortium.Teleost fish models in membrane transport research: the PEPT1(SLC15A1) H+-oligopeptide transporter as a case study.Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.Epithelial transport in inflammatory bowel diseases.Drug transporters in the nasal epithelium: an overview of strategies in targeted drug delivery.Getting across the cell membrane: an overview for small molecules, peptides, and proteins.Physiological and biochemical aspects of methionine isomers and a methionine analogue in broilers.Expression of small intestinal nutrient transporters in embryonic and posthatch turkeys.Collagen peptide ingestion alters lipid metabolism-related gene expression and the unfolded protein response in mouse liver.Nature and uses of fluorescent dyes for drug transporter studies.

P2860

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P2860

Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.

http://www.wikidata.org/entity/Q36700240

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Proton-coupled oligopeptide tr ...... and pathological implications.

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J.MAM.2012.11.003

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Molecular Aspects of Medicine

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Proton-coupled oligopeptide tr ...... and pathological implications.

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Benjamin Clémençon

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David E Smith

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Matthias A Hediger

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P2860

The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

The intestinal peptide transporter PEPT1 is involved in food intake regulation in mice fed a high-protein diet

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2

Cloning and characterization of a pH-sensing regulatory factor that modulates transport activity of the human H+/peptide cotransporter, PEPT1

The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology

The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction

Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function

Genetic variant Arg57His in human H+/peptide cotransporter 2 causes a complete loss of transport function

Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions

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10.1016/J.MAM.2012.11.003

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2-3

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