From calcium blips to calcium puffs: theoretical analysis of the requirements for interchannel communication
about
Role of elementary Ca(2+) puffs in generating repetitive Ca(2+) oscillations.STEPS: efficient simulation of stochastic reaction-diffusion models in realistic morphologiesSimple data-driven models of intracellular calcium dynamics with predictive power.The number and spatial distribution of IP3 receptors underlying calcium puffs in Xenopus oocytesIntra-cluster percolation of calcium signalsThe spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves.A simple sequential-binding model for calcium puffs.Quantifying calcium fluxes underlying calcium puffs in Xenopus laevis oocytes.Calcium domains around single and clustered IP3 receptors and their modulation by buffers.Inositol trisphosphate receptor Ca2+ release channels.Termination of calcium puffs and coupled closings of inositol trisphosphate receptor channels.Stochastic properties of Ca(2+) release of inositol 1,4,5-trisphosphate receptor clusters.Saltatory and continuous calcium waves and the rapid buffering approximationDistinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.Multi-scale data-driven modeling and observation of calcium puffs.Termination of Ca²+ release for clustered IP₃R channels.Unitary Ca(2+) current through recombinant type 3 InsP(3) receptor channels under physiological ionic conditions.Optimal ion channel clustering for intracellular calcium signaling.Modeling the statistics of elementary calcium release eventsModelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.Inositol (1,4,5)-trisphosphate receptor microarchitecture shapes Ca2+ puff kineticsCalcium oscillations.Analysis of puff dynamics in oocytes: interdependence of puff amplitude and interpuff interval.'Trigger' events precede calcium puffs in Xenopus oocytesModulation of elementary calcium release mediates a transition from puffs to waves in an IP3R cluster model.Hybrid stochastic and deterministic simulations of calcium blips.Calcium waves in a grid of clustered channels with synchronous IP3 binding and unbinding.Functional Role of Intracellular Calcium Receptor Inositol 1,4,5-Trisphosphate Type 1 in Rat Hippocampus after Neonatal AnoxiaMode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels.Tandem gramicidin channels cross-linked by streptavidin.Ryanodine receptor allosteric coupling and the dynamics of calcium sparksStochastic aspects of oscillatory Ca2+ dynamics in hepatocytes.Modeling Ca2+ feedback on a single inositol 1,4,5-trisphosphate receptor and its modulation by Ca2+ buffers.Communication shapes sensory response in multicellular networksLocalization and socialization: experimental insights into the functional architecture of IP3 receptorsTargeting and clustering of IP3 receptors: key determinants of spatially organized Ca2+ signals.Spatiotemporal organization of Ca dynamics: a modeling-based approach.Mitochondrial organization and Ca2+ uptake.Calcium signaling in the liverDetermining the Roles of Inositol Trisphosphate Receptors in Neurodegeneration: Interdisciplinary Perspectives on a Complex Topic.
P2860
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P2860
From calcium blips to calcium puffs: theoretical analysis of the requirements for interchannel communication
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
From calcium blips to calcium ...... for interchannel communication
@ast
From calcium blips to calcium ...... for interchannel communication
@en
type
label
From calcium blips to calcium ...... for interchannel communication
@ast
From calcium blips to calcium ...... for interchannel communication
@en
prefLabel
From calcium blips to calcium ...... for interchannel communication
@ast
From calcium blips to calcium ...... for interchannel communication
@en
P2093
P2860
P356
P1476
From calcium blips to calcium ...... for interchannel communication
@en
P2093
P2860
P304
13750-13755
P356
10.1073/PNAS.96.24.13750
P407
P577
1999-11-01T00:00:00Z