Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion.
about
Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trialRapid acid extrusion response triggered by alpha(1) adrenoceptor in CHO cellsTranslocation of the Na+/H+ exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signallingRegulation of cardiac sarcolemmal Na+/H+ exchanger activity by endogenous ligands. Relevance to ischemia.Na+/H+ exchangers. Molecular diversity and relevance to heart.Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy studyThe expanding family of eucaryotic Na(+)/H(+) exchangers.Na(+)/H(+) exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions.Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRIActivity of the Na+/H+ exchanger contributes to cardiac damage following ischaemia and reperfusion.Pharmacology and clinical assessment of cariporide for the treatment coronary artery diseases.A cell-based phenotypic assay to identify cardioprotective agentsExperimental generation and computational modeling of intracellular pH gradients in cardiac myocytes.Therapeutic potential of Na-H exchange inhibitors for the treatment of heart failure.Endothelial Na+/H+ exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal.Activation of microglia depends on Na+/H+ exchange-mediated H+ homeostasis.Inhibiting the Na+/H+ exchanger reduces reperfusion injury: a small animal MRI study.Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury.Effects and interaction, of cariporide and preconditioning on cardiac arrhythmias and infarction in rat in vivo.Involvement of the Na+/H+ exchanger in membrane phosphatidylserine exposure during human platelet activation.NHE isoform switching and KChIP2 upregulation in aging porcine atria.Is timing everything? Therapeutic potential of modulators of cardiac Na(+) transporters.pH-Dependence of extrinsic and intrinsic H(+)-ion mobility in the rat ventricular myocyte, investigated using flash photolysis of a caged-H(+) compound.Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools.Inhibition of Na⁺-H⁺ exchange as a mechanism of rapid cardioprotection by resveratrol.pH-Regulated Na(+) influx into the mammalian ventricular myocyte: the relative role of Na(+)-H(+) exchange and Na(+)-HCO Co-transport.Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger.Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.Physiological role and regulation of the Na+/H+ exchanger.The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury.AVE4454B--a novel sodium-hydrogen exchanger isoform-1 inhibitor--compared less effective than cariporide for resuscitation from cardiac arrest.The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes.Excitation-contraction coupling and mitochondrial energetics.Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642).Microglial ion channels as potential targets for neuroprotection in Parkinson's disease.Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis.Recent advances in the molecular and functional characterization of acid/base and electrolyte transporters in the basolateral membranes of gastric and duodenal epithelial cells.Na+/H+ exchangers.Role of pHi, and proton transporters in oncogene-driven neoplastic transformation.Myocardial protection from ischemia-reperfusion injury post coronary revascularization.
P2860
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P2860
Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@ast
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@en
type
label
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@ast
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@en
prefLabel
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@ast
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@en
P2093
P1476
Protective effects of HOE642, ...... iac ischaemia and reperfusion.
@en
P2093
Counillon L
Gögelein H
Schölkens BA
Weichert A
P304
P356
10.1016/0008-6363(96)88579-8
P577
1995-02-01T00:00:00Z