Modulation of interferon signaling in human fibroblasts by phorbol esters.
about
Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.A nuclear tyrosine phosphatase downregulates interferon-induced gene expression.Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase.Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells.Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage.In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate.Type I interferons activate apoptosis in a Jurkat cell variant by caspase-dependent and independent mechanismsA PI-3 kinase-dependent, Stat1-independent signaling pathway regulates interferon-stimulated monocyte adhesion.Identification of a novel conserved motif in the STAT family that is required for tyrosine phosphorylation.
P2860
Q28609564-5E3789EF-1FB0-449E-AA9E-2ACC89593F9CQ35620265-71202FC3-B930-4D91-A951-5140A4A40C26Q36647166-19615603-D7C5-4B43-9AAC-C4E425602B26Q36827566-37CBAAFA-5EC2-4115-8D47-5F4436F8CAE0Q40018479-A295CEBE-4BA9-42F6-B9F9-108DF0484774Q40619569-88217B7E-8232-423D-98BD-524C06864D68Q40817313-53E60E41-1B2C-4E37-B7A7-36D8773094E9Q41848518-8F051D9C-7B96-4CCF-A5A3-81418064CC9CQ41863692-B7C59866-A054-4FE2-AB25-1B7D5AB35D7AQ42199581-334D868B-9B42-48D5-8D42-7B8CA0D639BDQ44378771-C5421939-CC3C-4B4C-AD93-86F0191E9E0DQ44727139-A4D95F63-76E8-4EFA-89E7-17CE38F23F88
P2860
Modulation of interferon signaling in human fibroblasts by phorbol esters.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@ast
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@en
type
label
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@ast
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@en
prefLabel
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@ast
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@en
P2093
P2860
P356
P1476
Modulation of interferon signaling in human fibroblasts by phorbol esters.
@en
P2093
Finbloom DS
Hackett RH
Igarashi K
Petricoin EF 3rd
P2860
P304
P356
10.1128/MCB.12.10.4486
P407
P577
1992-10-01T00:00:00Z