Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
about
The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor SurvivalTarget identification for biologically active small molecules using chemical biology approaches.Palmitoylation of proteins in cancer.Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives.New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound.Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy.The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
P2860
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P2860
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@ast
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@en
type
label
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@ast
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@en
prefLabel
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@ast
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@en
P2093
P2860
P356
P1476
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
@en
P2093
Amy E Owen
Andrew Lemoff
Bethany Cross
Bruce A Posner
Deepak Nijhawan
Hamid Mirzaei
John S McKnight
Jordan M Hanson
Jose R Moreno
Joseph M Ready
P2860
P2888
P304
P356
10.1038/NCHEMBIO.2016
P577
2016-02-01T00:00:00Z