Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
about
Modulation of the matrix redox signaling by mitochondrial Ca(2.)Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsGlutaredoxin-2 is required to control oxidative phosphorylation in cardiac muscle by mediating deglutathionylation reactions.Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats.Glutaredoxin 2 (Grx2) gene deletion induces early onset of age-dependent cataracts in miceLow birth weight is associated with adiposity, impaired skeletal muscle energetics and weight loss resistance in mice.Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species.Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria.Glutaredoxin 2a overexpression in macrophages promotes mitochondrial dysfunction but has little or no effect on atherogenesis in LDL-receptor null mice.Mitochondrial uncoupling in skeletal muscle by UCP1 augments energy expenditure and glutathione content while mitigating ROS production.Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions.S-glutathionylation reactions in mitochondrial function and diseaseGlutathionyl systems and metabolic dysfunction in obesity.Induction of mitochondrial reactive oxygen species production by GSH mediated S-glutathionylation of 2-oxoglutarate dehydrogenase.Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic β-cell dysfunction and death in vitro.Detailed Biochemical and Bioenergetic Characterization of FBXL4-Related Encephalomyopathic Mitochondrial DNA Depletion.A Cistanches Herba Fraction/ β -Sitosterol Causes a Redox-Sensitive Induction of Mitochondrial Uncoupling and Activation of Adenosine Monophosphate-Dependent Protein Kinase/Peroxisome Proliferator-Activated Receptor γ Coactivator-1 in C2C12 MyotubesProtein S-glutathionlyation links energy metabolism to redox signaling in mitochondria.A novel amino acid and metabolomics signature in mice overexpressing muscle uncoupling protein 3.Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies.Choline and dimethylglycine produce superoxide/hydrogen peroxide from the electron transport chain in liver mitochondria.Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells.Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria.Expression of thioredoxins and glutaredoxins in human hepatocellular carcinoma: correlation to cell proliferation, tumor size and metabolic syndrome.Protein S-glutathionylation lowers superoxide/hydrogen peroxide release from skeletal muscle mitochondria through modification of complex I and inhibition of pyruvate uptake.
P2860
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P2860
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@ast
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@en
type
label
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@ast
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@en
prefLabel
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@ast
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@en
P2093
P2860
P356
P1476
Glutaredoxin-2 is required to control proton leak through uncoupling protein-3.
@en
P2093
Brittany Beauchamp
Jian Ying Xuan
Marjorie Lou
Mary-Ellen Harper
Ryan J Mailloux
P2860
P304
P356
10.1074/JBC.M112.442905
P407
P577
2013-01-18T00:00:00Z