Characterization of pp85, a target of oncogenes and growth factor receptors
about
Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulationAutophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoGenetic analysis of a phosphatidylinositol 3-kinase SH2 domain reveals determinants of specificityCloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytesA Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling.The v-Src SH3 domain binds phosphatidylinositol 3'-kinase.Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes.Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity.Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteinsPhosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinaseCell transformation by the middle T-antigen of polyoma virus.Identification and characterization of the hamster polyomavirus middle T antigen.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosineTransformation-defective mutants of polyomavirus middle T antigen associate with phosphatidylinositol 3-kinase (PI 3-kinase) but are unable to maintain wild-type levels of PI 3-kinase products in intact cellsEvidence that the middle T antigen of polyomavirus interacts with the membrane skeletonA completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activityLessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.Inhibition of stem cell factor- and nerve growth factor-induced morphological change by wortmannin in mast cells.Polyomavirus small t antigen prevents retinoic acid-induced retinoblastoma protein hypophosphorylation and redirects retinoic acid-induced G0 arrest and differentiation to apoptosis.Multiple change in E2F function and regulation occur upon muscle differentiation.Requirement for phosphatidylinositol 3-kinase in epidermal growth factor-induced AP-1 transactivation and transformation in JB6 P+ cells.Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase.Phosphatidylinositol 3-kinase regulates proliferation of RAW 264.7 macrophages.PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange.Relationship of growth stimulated by lithium, estradiol, and EGF to phospholipase C activity in MCF-7 human breast cancer cells.Platelet-derived growth factor induces phosphatidylinositol 3-kinase release from the middle T-pp60c-src complex and association with the platelet-derived growth factor receptor.Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns.Quantitation of extracellular UTP using a sensitive enzymatic assay.Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo.Purification and characterization of phosphatidylinositol 4-kinase from human erythrocyte membranes.
P2860
Q24293143-37DD8A13-645C-4A2A-8A3E-8F076E6E0C10Q24533731-1B229DA8-B135-4023-B9B2-68B2FCAABEB5Q24610035-6DB26BF7-E42E-4105-AFB1-EFBBF0D8C92BQ24629213-8046EFFA-52BE-4E54-9619-0F6949C158A6Q28250031-4F63E0A6-D7CA-41D3-8D85-2E2DA2A3FA36Q30008815-820ABC6B-8831-433A-AE22-E55059434570Q30194840-6B7A0B55-678D-444F-B553-0B4137E969BAQ30450318-6635DC10-D58B-4C92-944F-8C5B498F28F4Q33627470-3A65C62F-FB68-4587-86C6-25822E0D0FE7Q33782069-977CFEF7-53C5-4AE9-8AB3-F76CE0A8EC53Q33922224-01935B15-6087-4C39-AF9F-AB39738FB998Q34468798-802CF8E8-2A1E-4FCB-B05F-CCA43A2F3402Q34580770-9D661025-2E77-4783-86E6-86127B5736A8Q34985587-57A90F96-4B36-49FB-9BF8-C5B11B2593DAQ35000523-A0794A96-D971-4260-BC23-EA1CE0431190Q35861223-DB63B4B2-0C67-4B43-A474-BF6FFC2D875DQ36676193-0EC76BAF-86DA-4B8C-818F-F24669C641C8Q36685553-E3A1C063-59C1-434B-B8FD-66D0627047CFQ36693102-65A3C9EF-8359-485C-8CB3-351D4B538DA6Q36694402-AFDF7F76-0FE6-4C35-BB57-F72E6A63548AQ36783132-A95F9F6D-9642-4E85-89AB-4BE9E8FE7654Q37330814-1581FB8B-9CD4-4624-BB6F-12A0DCE3D5AEQ38527946-44E39605-AB6E-4D26-B4EB-F311E9F1A866Q39606202-3F9E6A23-930D-4216-ADC5-FF7F83BFDC64Q40016087-8A7F1BCE-5B71-45C4-B132-E04681B486CFQ40020281-9D413684-46A8-474C-AF5D-4A93BECDE8B2Q40309214-33903135-E0AA-4265-ABBF-B9FFD3146994Q40770573-CF4810DE-8E1A-4DE2-BACA-B9076F00B41CQ40790718-5C24D293-B76C-4764-92F6-90F98CD78ECEQ41204520-7ED8B936-3547-4108-BB15-3769D4CAE747Q41341547-373FC0C3-478E-4974-942E-9F8ADB847AF1Q41507086-FD8B29CC-A4EB-4A56-A2A5-24C21D8A4FD3Q41787609-7612ACC1-D8BA-4B43-A94B-1C5FD9951863Q41912161-7263C24E-D9B7-45AC-A850-0D07352B7019Q42809738-0522778E-7B6D-436F-A704-4BCF7DF28260Q44493667-BC33BD7B-9A0D-47C2-ABBA-23DDAF0A344F
P2860
Characterization of pp85, a target of oncogenes and growth factor receptors
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Characterization of pp85, a target of oncogenes and growth factor receptors
@ast
Characterization of pp85, a target of oncogenes and growth factor receptors
@en
type
label
Characterization of pp85, a target of oncogenes and growth factor receptors
@ast
Characterization of pp85, a target of oncogenes and growth factor receptors
@en
prefLabel
Characterization of pp85, a target of oncogenes and growth factor receptors
@ast
Characterization of pp85, a target of oncogenes and growth factor receptors
@en
P2093
P2860
P356
P1476
Characterization of pp85, a target of oncogenes and growth factor receptors
@en
P2093
B S Schaffhausen
T M Roberts
P2860
P304
P356
10.1128/MCB.10.6.2909
P407
P577
1990-06-01T00:00:00Z