Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. - Wikidata - awgldk - TriplyDB

Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.

Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.

http://www.wikidata.org/entity/Q36713660

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Reciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3 ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain.Spatial analysis of expression patterns predicts genetic interactions at the mid-hindbrain boundary DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility Dissection of the Auditory Bulla in Postnatal Mice: Isolation of the Middle Ear Bones and Histological Analysis.p-MAPK1/3 and DUSP6 regulate epididymal cell proliferation and survival in a region-specific manner in mice.Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates.Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.Generation of FGF reporter transgenic zebrafish and their utility in chemical screens.Hearing loss in a mouse model of Muenke syndrome Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium.Expression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development.In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase.Cooperative and independent functions of FGF and Wnt signaling during early inner ear development.Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages.New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling Signaling gradients during paraxial mesoderm development.The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma.Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system.A missense mutation in Fgfr1 causes ear and skull defects in hush puppy mice.Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube.Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism.Evolution of the new vertebrate head by co-option of an ancient chordate skeletal tissue.The Fibroblast Growth Factor signaling pathway Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma Three-step method for proliferation and differentiation of human embryonic stem cell (hESC)-derived male germ cells.MAPK phosphatase 7 regulates T cell differentiation via inhibiting ERK-mediated IL-2 expression.Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation Modelling coupled oscillations in the Notch, Wnt, and FGF signaling pathways during somitogenesis: a comprehensive mathematical model.Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells Genetics of the dentofacial variation in human malocclusion Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways Regulation of cranial morphogenesis and cell fate at the neural crest-mesoderm boundary by engrailed 1.Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells.

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P2860

Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.

http://www.wikidata.org/entity/Q36713660

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2007 nî lūn-bûn

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Dusp6 (Mkp3) is a negative fee ...... ling during mouse development.

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Chaoying Li

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Daryl A Scott

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Ekaterina Hatch

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Suzanne L Mansour

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Xiaoyan Tian

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P2860

MAP kinase phosphatases

Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases

Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase

Cellular signaling by fibroblast growth factor receptors

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase

Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae.

Fibroblast growth factors, their receptors and signaling

Roles of FGF signaling in skeletal development and human genetic diseases

Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations

Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear

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