Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking.
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Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclaseInterfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity.Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content.The solution structure of the transducin-α-uncoordinated 119 protein complex suggests occlusion of the Gβ₁γ₁-binding sites.Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction.Heat Shock Protein 90 Associates with the Per-Arnt-Sim Domain of Heme-free Soluble Guanylate Cyclase: IMplications for Enzyme Maturation.YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase.Probing the Molecular Mechanism of Human Soluble Guanylate Cyclase Activation by NO in vitro and in vivo.Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.Nitric oxide-induced conformational changes in soluble guanylate cyclaseThe chemistry and biology of soluble guanylate cyclase stimulators and activators.Structures of soluble guanylate cyclase: implications for regulatory mechanisms and drug development.Regulation of sGC via hsp90, Cellular Heme, sGC Agonists, and NO: New Pathways and Clinical Perspectives.Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor.Nitric oxide activation of guanylate cyclase pushes the α1 signaling helix and the β1 heme-binding domain closer to the substrate-binding site.Inhibition of soluble guanylyl cyclase by small molecules targeting the catalytic domainDiscovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase.Structure/function of the soluble guanylyl cyclase catalytic domain.Searching for 3D structural models from a library of biological shapes using a few 2D experimental images
P2860
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P2860
Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
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name
Molecular model of a soluble g ...... ng and chemical cross-linking.
@ast
Molecular model of a soluble g ...... ng and chemical cross-linking.
@en
type
label
Molecular model of a soluble g ...... ng and chemical cross-linking.
@ast
Molecular model of a soluble g ...... ng and chemical cross-linking.
@en
prefLabel
Molecular model of a soluble g ...... ng and chemical cross-linking.
@ast
Molecular model of a soluble g ...... ng and chemical cross-linking.
@en
P2093
P2860
P356
P1433
P1476
Molecular model of a soluble g ...... ng and chemical cross-linking.
@en
P2093
Andrzej Weichsel
Aqeel Ahmed
Bradley G Fritz
Jacqueline L Brailey
Linda Breci
Sue A Roberts
Wenzhou Li
William R Montfort
P2860
P304
P356
10.1021/BI301570M
P407
P577
2013-02-15T00:00:00Z