Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
about
Conserved CTCF insulator elements flank the mouse and human beta-globin lociMolecular and phenotypic aspects of CHD7 mutation in CHARGE syndromeRhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion.A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region.In vivo protein-DNA interactions at hypersensitive site 3 of the human beta-globin locus control region.The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells.Developmental stage differences in chromatin subdomains of the beta-globin locus.Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences.Function of GATA transcription factors in hydroxyurea-induced HEL cells.An Erythroid-Specific Chromatin Opening Element Increases β-Globin Gene Expression from Integrated Retroviral Gene Transfer Vectors.Beta-globin locus control region HS2 and HS3 interact structurally and functionallyExpression of GATA-1 in a non-hematopoietic cell line induces beta-globin locus control region chromatin structure remodeling and an erythroid pattern of gene expression.Structure and function of the murine beta-globin locus control region 5' HS-3.Nucleosome and transcription activator antagonism at human beta-globin locus control region DNase I hypersensitive sites.Long-range disruption of gene expression by a selectable marker cassette.Use of yeast artificial chromosomes (YACs) for studying control of gene expression: correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell linesGenomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.Protein-DNA interactions in vivo of an erythroid-specific, human beta-globin locus enhancer.Enhancer-dependent transcriptional oscillations in mouse erythroleukemia cells.Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter.Meiotic double-strand breaks in yeast artificial chromosomes containing human DNAAnalysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.Comparative analysis of the locus control region of the rabbit beta-like gene cluster: HS3 increases transient expression of an embryonic epsilon-globin gene.The mouse M-lysozyme gene domain: identification of myeloid and differentiation specific DNasel hypersensitive sites and of a 3'-cis acting regulatory element.The mouse beta-globin locus control region: hypersensitive sites 3 and 4.NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human beta-globin locus control region.A (GATA)(7) motif located in the 5' boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells.Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcriptionIn vivo formation of a human beta-globin locus control region core element requires binding sites for multiple factors including GATA-1, NF-E2, erythroid Kruppel-like factor, and Sp1.Reduced beta-globin gene expression in adult mice containing deletions of locus control region 5' HS-2 or 5' HS-3.Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins.
P2860
Q24537420-06F1FFA4-07CE-47FD-BEDC-4D061132AE7DQ24634411-87F1F0FF-F23D-4080-94CA-36FDDA4FF08CQ30658223-5D128B20-1F86-409C-9139-890550A97977Q31621466-F43AC451-733D-4959-A7CB-173F89DCC5D8Q33611389-9ECC7731-4ACC-45AE-AB59-0F4C9016B7BEQ33780942-EAB319A0-A487-4E93-AF84-3A8E042C81ACQ33782323-E393DCA0-7AF9-4F07-BDAE-7927D30581EEQ33910867-4943BF7D-77EA-4A6E-A530-01C3E3849546Q34109105-FFC3D355-456B-48F2-81D7-D6BF5EBE364DQ34586740-2C9408D5-6C80-4F63-BF8E-AAB2F87DAD1FQ34771386-E4A102E6-1F2B-436A-A58E-2B2C72AB2296Q35728245-F14E6ED7-DD98-4D29-BBA7-A24659C4BC44Q35933696-93006866-705C-427B-8FDD-DA4EE79588ECQ36082870-EA9C0E06-E842-43D0-A50C-494AC62DE08AQ36687936-174693CD-FCAB-40EA-811A-BD19FA2DA2B4Q36695335-4C34FB2B-D727-46E4-9F49-607348896D06Q37150865-E1856863-6F1C-45BF-B0B8-2D1EB443D87CQ37290024-63B50BED-50E4-4B7A-8582-6F631796C35FQ37600735-611D64AB-01D6-43F0-8EC6-C30BF255CD7FQ39446231-A8E80A2A-5E73-4609-8B9C-388676FFF286Q39717999-408C217B-57B4-48E7-930F-2E03A1C49C21Q39723780-58FAEBC2-69E3-4C1D-B787-4F5C04B2866CQ40019012-4055232D-89B7-446C-AFEB-77A449476DE5Q40405841-3DAF8801-A7E9-436C-9ECD-0A70555FE8A6Q40421930-FBC2DACE-DE1B-4A6B-902D-68C1B7FD0F0EQ40535343-BC55B231-DEF7-4112-8AC0-E317E7006E05Q40805375-C675DACC-EEFE-41F1-9249-19080DE74E95Q40862597-F69D32FB-4820-4C12-9601-37B255F1843FQ41891258-44CB74E3-288E-4EB3-9481-FF1BE41BEC68Q43576548-D55C889F-CE62-438A-8C7F-DBF082D98A60Q47824799-2939EE4C-F9B8-4428-8251-681F5AE164FAQ52196730-4CF2B78A-23A8-4457-9D10-2054D635ACFA
P2860
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@ast
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@en
type
label
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@ast
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@en
prefLabel
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@ast
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@en
P2093
P2860
P356
P1476
Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain.
@en
P2093
A I Skoultchi
C L Schildkraut
P2860
P304
P356
10.1128/MCB.10.8.4324
P407
P577
1990-08-01T00:00:00Z