Cellular proteolytic systems in P450 degradation: evolutionary conservation from Saccharomyces cerevisiae to mammalian liver.
about
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligasesUbiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitinationA role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradationMultisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction.Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance.Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol.Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal.CHIP and gp78-mediated ubiquitination of CYP3A4: Implications for the pharmacology of anticancer agents.MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyInfluence of protein-protein interactions on the cellular localization of cytochrome P450.Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum.Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport.Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.
P2860
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P2860
Cellular proteolytic systems in P450 degradation: evolutionary conservation from Saccharomyces cerevisiae to mammalian liver.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@ast
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@en
type
label
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@ast
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@en
prefLabel
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@ast
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@en
P2860
P356
P1476
Cellular proteolytic systems i ...... cerevisiae to mammalian liver.
@en
P2093
Maria Almira Correia
Mingxiang Liao
P2860
P356
10.1517/17425255.3.1.33
P407
P577
2007-02-01T00:00:00Z