Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
about
Mechanisms of acetaminophen-induced liver necrosisCase Characterization, Clinical Features and Risk Factors in Drug-Induced Liver InjuryInroads to predict in vivo toxicology-an introduction to the eTOX ProjectKey Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation PlansTranslating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)Natural terpenes prevent mitochondrial dysfunction, oxidative stress and release of apoptotic proteins during nimesulide-hepatotoxicity in ratsBioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In VitroA New Structure-Activity Relationship (SAR) Model for Predicting Drug-Induced Liver Injury, Based on Statistical and Expert-Based Structural AlertsEvaluation of the Potential Risk of Drugs to Induce Hepatotoxicity in Human-Relationships between Hepatic Steatosis Observed in Non-Clinical Toxicity Study and Hepatotoxicity in HumansSuppression of ROS generation by 4,4-diaminodiphenylsulfone in non-phagocytic human diploid fibroblastsMechanisms of immune-mediated liver injury.Mitochondrial DNA levels in Huntington disease leukocytes and dermal fibroblasts.Drug-induced liver injury in older adults.Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria.Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicityFactors affecting drug-induced liver injury: antithyroid drugs as instances.Hepatoprotective effect of Cymbopogon citratus aqueous extract against hydrogen peroxide-induced liver injury in male ratsIdentification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells.Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.Mitochondrial pharmacology: electron transport chain bypass as strategies to treat mitochondrial dysfunction.Age-related changes in the hepatic pharmacology and toxicology of paracetamol.Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.Endogenous interleukin-4 regulates glutathione synthesis following acetaminophen-induced liver injury in micePolymorphism of PXR gene associated with the increased risk of drug-induced liver injury in Indonesian pulmonary tuberculosis patients.Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria.Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity.Repeated exposure to modern volatile anaesthetics may cause chronic hepatitis as well as acute liver injuryImmunogenomics reveal molecular circuits of diclofenac induced liver injury in miceAssessment of drug-induced liver injury in clinical practice.Current concepts of mechanisms in drug-induced hepatotoxicity.Mechanism-based bioanalysis and biomarkers for hepatic chemical stress.Drug-induced liver injury: insights from genetic studies.Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management.Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicityBiomarkers for drug-induced liver injury.Pharmacogenetics of drug-induced liver injury.Mechanisms of drug toxicity and relevance to pharmaceutical development.Animal models of idiosyncratic drug-induced liver injury--current status.Idiosyncratic reactions and metabolism of sulfur-containing drugs.Evaluation of drug-induced injury and human response in precision-cut tissue slices.
P2860
Q24629891-044DBEBE-E870-446D-81E8-2AABADC0B75EQ26749054-232272BE-7916-42C8-8CD7-FF37CA794134Q26852917-6E982347-3A60-4B14-8EF9-64AE9CB63EC9Q28075991-8211746B-943F-4110-9A56-790440473407Q28478443-27B09452-64A3-437F-9B80-4BC695A20C00Q28482088-017EF3B4-4B72-437E-BB8F-16DD84702291Q28552429-8C755A44-7C75-4197-AC37-6CF14EB01CAFQ28820944-B7F8C1A5-D45D-4E23-95FB-AB4F5BAB4F09Q33624685-94D1DCD6-5571-48F4-8959-68057C35DECFQ33751396-AC4E3A4E-F37E-4184-A57E-44D83EA492ABQ33856306-2B353E9A-2A47-41A3-A5CA-F5882C8913E6Q33890630-4A045D01-7DB7-4266-BE9E-4714E1422803Q33949227-23C2B43A-6F3C-406B-B336-C596E740E831Q33954265-3FA6B7A8-A5A8-45EB-8205-988376BA5695Q34200596-FE85ECFF-89B4-4AB1-BCE6-B40B0CDDAA3DQ34339590-CBD1412C-9D45-45F6-9C7A-54BA5CECA6B3Q34368508-B5DCB629-78C7-4480-8441-837876A1436FQ34534111-1A99B862-F88F-4918-8716-88F2A08AE7FEQ34663837-2AFD69F5-A867-4D03-B043-8C070C3E48B8Q34988040-72BF7A9F-3E04-4935-A2B7-B7E07B71544AQ35101500-D557AA9C-4E62-4A61-BF3E-3FF8414E467CQ35185719-F078C436-BEBD-4DEA-9242-9DAEFFB6B6B1Q35675464-0AE88CAD-FC1E-4958-BF6B-EF90FA279114Q35791410-DB63554D-CA05-49C5-BDC5-F7A208B6578CQ36247086-116560FD-6222-4E14-A590-058040B6B70DQ36375764-B663C919-80BA-4044-916E-3CBF1307C67CQ36884643-BE53E198-158E-41A3-80F4-F4662154488BQ37046776-17A7EAA8-C107-46E0-A721-F2180B27CA86Q37114105-B274FD59-90BB-4AAE-A33E-294EA6693AB2Q37394799-A3D71B64-7305-4C88-AE28-9A268B0AD817Q37557613-19BA2091-9D10-438A-B5D2-EF90624EE5EEQ37598897-9C195751-73DA-482D-A61C-AA386AE0F39EQ37613267-94D81D36-79FB-4297-9854-13AD6027FDF5Q37656707-D5770509-8530-4C19-B684-894402B246BFQ37720754-5FD34EE4-06EC-4817-9227-8FD9D9F6C0D2Q37770487-257FCDA6-9134-47C1-9316-397E89B5455CQ37803316-4CD50A79-0F9F-45D7-883F-D9EAEC70649FQ37897219-E862637F-6E04-4B2A-959A-FEB940DED692Q37991021-4D211FA3-EF75-4B48-8E26-A89AC84309FFQ38055199-705C6E8B-4081-4D89-8AB0-96FF9CE4D2DD
P2860
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@ast
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@en
type
label
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@ast
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@en
prefLabel
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@ast
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@en
P1476
Mitochondrial abnormalities--a link to idiosyncratic drug hepatotoxicity?
@en
P2093
Priscilla L K Lim
Urs A Boelsterli
P304
P356
10.1016/J.TAAP.2006.12.013
P577
2006-12-22T00:00:00Z