Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer. - Wikidata - awgldk - TriplyDB

Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.

Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.

http://www.wikidata.org/entity/Q36727390

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Targeting dormant micrometastases: rationale, evidence to date and clinical implications Metastatic mechanisms in follicular cell-derived thyroid cancer Mechanisms of disseminated cancer cell dormancy: an awakening field EMT, CTCs and CSCs in tumor relapse and drug-resistance Autotaxin: structure-function and signaling Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers.Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Molecular pathways: niches in metastatic dormancy Autotaxin-lysophosphatidic acid signaling axis mediates tumorigenesis and development of acquired resistance to sunitinib in renal cell carcinoma.TLR4 ligand/H₂O₂ enhances TGF-β1 signaling to induce metastatic potential of non-invasive breast cancer cells by activating non-Smad pathways.Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis β3 integrin promotes TGF-β1/H2O2/HOCl-mediated induction of metastatic phenotype of hepatocellular carcinoma cells by enhancing TGF-β1 signaling.Metabolic Signatures of Human Breast Cancer.Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer.Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling.Mechanisms linking obesity and cancer Breast cancer metastasis: issues for the personalization of its prevention and treatment.Roadblocks to translational advances on metastasis research.The dormancy dilemma: quiescence versus balanced proliferation.Promising pharmacological directions in the world of lysophosphatidic Acid signaling.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.Eicosopentaneoic Acid and Other Free Fatty Acid Receptor Agonists Inhibit Lysophosphatidic Acid- and Epidermal Growth Factor-Induced Proliferation of Human Breast Cancer Cells Surgical margins in the veterinary cancer patient.Inhibition of nm23-H1 gene expression in chronic myelogenous leukemia cells.Intracellular IL-37b interacts with Smad3 to suppress multiple signaling pathways and the metastatic phenotype of tumor cells.Modeling boundary conditions for balanced proliferation in metastatic latency.Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways.Metastasis awakening: targeting dormant cancer.Alpha conotoxin-BuIA globular isomer is a competitive antagonist for oleoyl-L-alpha-lysophosphatidic acid binding to LPAR6; A molecular dynamics study.Tumor cell dormancy as an adaptive cell stress response mechanism.Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways.An Lysophosphatidic Acid Receptors 1 and 3 Axis Governs Cellular Senescence of Mesenchymal Stromal Cells and Promotes Growth and Vascularization of Multiple Myeloma.Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target.Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer-Challenges and Opportunities.Overexpression and Functional Stabilization of Recombinant Human Lysophosphatidic Acid Receptor 1 Using an Amphiphatic Polymer

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Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.

http://www.wikidata.org/entity/Q36727390

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2012 nî lūn-bûn

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Effect of inhibition of the ly ...... tic dormancy in breast cancer.

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Effect of inhibition of the ly ...... tic dormancy in breast cancer.

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Effect of inhibition of the ly ...... tic dormancy in breast cancer.

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Journal of the National Cancer Institute

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Effect of inhibition of the ly ...... tic dormancy in breast cancer.

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Christine E Horak

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David J Liewehr

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Diane Palmieri

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Fernando Vidal-Vanaclocha

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Jean-Claude A Marshall

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Joji Nakayama

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Joshua W Collins

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Mary Albaugh

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Maryse Barbier

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Maximilien Murone

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A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

Lysophosphatidic acid receptors

Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1

The emerging role of lysophosphatidic acid in cancer

RhoGDI2 is an invasion and metastasis suppressor gene in human cancer

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells

Tumor metastasis: mechanistic insights and clinical challenges

Learning therapeutic lessons from metastasis suppressor proteins.

Metastasis: a therapeutic target for cancer.

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1306-1319

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10.1093/JNCI/DJS319

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17

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104

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2012-08-21T00:00:00Z

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230715082

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22911670

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3611817

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