Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study
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A statin-dependent QTL for GATM expression is associated with statin-induced myopathyGenetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trialsCandidate-Gene Study of Functional Polymorphisms in SLCO1B1 and CYP3A4/5 and the Cholesterol-Lowering Response to SimvastatinHeritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis.Poly-omic prediction of complex traits: OmicKriging.Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary aIdentifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine.Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.Prediction of cardiovascular events in statin-treated stable coronary patients of the treating to new targets randomized controlled trial by lipid and non-lipid biomarkersVery low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials.Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma ConcentrationsShould Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?Effects of phenotypic and genotypic factors on the lipid responses to niacin in Chinese patients with dyslipidemia.SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization.THE CHALLENGES IN USING ELECTRONIC HEALTH RECORDS FOR PHARMACOGENOMICS AND PRECISION MEDICINE RESEARCHPharmacogenetics and cardiovascular disease--implications for personalized medicineStatin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner.SLCO1B1 Polymorphisms and Statin-Induced Myopathy.The Association between KIF6 Single Nucleotide Polymorphism rs20455 and Serum Lipids in Filipino-American WomenPharmacogenomics of lipid-lowering therapies.Lipid-lowing pharmacogenomics in Chinese patients.Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin.Pharmacogenomics, lipid disorders, and treatment options.RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol.Common genetic risk factors for coronary artery disease: new opportunities for prevention?Seventeen years of statin pharmacogenetics: a systematic review.Personalized medicine: Genetic risk prediction of drug response.Pharmacogenetics of Lipid-Lowering Agents: Precision or Indecision Medicine?Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study.A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol loweringAssociation of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjectsGenes and cardiovascular risk.Pharmacogenetics of Lipid-Lowering Agents: an Update Review on Genotype-Dependent Effects of HDL-Targetingand Statin Therapies.A genetic risk score is significantly associated with statin therapy response in the elderly population.Effect of an SNP in SCAP gene on lipid-lowering response to rosuvastatin in Indian patients with metabolic syndrome.No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population.LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving StatinsPolymorphisms of SLCO1B1 rs4149056 and SLC22A1 rs2282143 are associated with responsiveness to acitretin in psoriasis patients
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P2860
Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Impact of common genetic varia ...... in the Heart Protection Study
@ast
Impact of common genetic varia ...... in the Heart Protection Study
@en
type
label
Impact of common genetic varia ...... in the Heart Protection Study
@ast
Impact of common genetic varia ...... in the Heart Protection Study
@en
prefLabel
Impact of common genetic varia ...... in the Heart Protection Study
@ast
Impact of common genetic varia ...... in the Heart Protection Study
@en
P2093
P2860
P356
P1476
Impact of common genetic varia ...... in the Heart Protection Study
@en
P2093
Alison Offer
Jane Armitage
Jemma C Hopewell
MRC/BHF Heart Protection Study Collaborative Group
Robert Clarke
Rory Collins
P2860
P304
P356
10.1093/EURHEARTJ/EHS344
P577
2012-10-24T00:00:00Z