Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas - Wikidata - awgldk - TriplyDB

Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas

Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas

http://www.wikidata.org/entity/Q36737930

about

Chromatin Dynamics in Vivo: A Game of Musical Chairs New developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in glioma Epigenetic Therapeutics: A New Weapon in the War Against Cancer Oncometabolites: tailoring our genes 2-Hydoxyglutarate: D/Riving Pathology in gLiomaS Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism Modulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells.Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.Emerging role of linker histone variant H1x as a biomarker with prognostic value in astrocytic gliomas. A multivariate analysis including trimethylation of H3K9 and H4K20.KDM5B is overexpressed in gastric cancer and is required for gastric cancer cell proliferation and metastasis.Hypoxia Induces Production of L-2-Hydroxyglutarate.What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer.Is glioblastoma an epigenetic malignancy?Metabolic modulation of epigenetics in gliomas.Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment.The evolving molecular genetics of low-grade glioma.Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.Epigenetics in NG2 glia cells.Epigenetic Determinants of Cancer.Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation.Epigenetics of Meningiomas.Altered global histone-trimethylation code and H3F3A-ATRX mutation in pediatric GBM.

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P2860

Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas

http://www.wikidata.org/entity/Q36737930

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2013 nî lūn-bûn

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name

Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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Journal of Neuropathology & Experimental Neurology

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Histone 3 lysine 9 trimethylat ...... as and high-grade astrocytomas

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P2093

Alexander R Judkins

http://www.w3.org/2001/XMLSchema#string

Arie Perry

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Chao Lu

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Craig B Thompson

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Daniel Gorovets

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Jason T Huse

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Joanna J Phillips

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Julia Kofler

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Lisa M Sullivan

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Mariarita Santi

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P2860

Regulation of chromatin structure by site-specific histone H3 methyltransferases

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

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oligodendroglioma

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