Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy
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Molecular targets for antiepileptic drug developmentThe neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse?Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes.What is orgasm? A model of sexual trance and climax via rhythmic entrainment.Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex.Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticusGenetic deletion of the neuronal glutamate transporter, EAAC1, results in decreased neuronal death after pilocarpine-induced status epilepticus.Transcriptome analysis in a rat model of L-DOPA-induced dyskinesiaThe importance of the excitatory amino acid transporter 3 (EAAT3)mRNA for the EAAC1 subtype of glutamate transporter is present in neuronal dendrites in vitro and dramatically increases in vivo after a seizure.Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasiaKlotho sensitivity of the neuronal excitatory amino acid transporters EAAT3 and EAAT4.Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1.The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease.Rosiglitazone Suppresses In Vitro Seizures in Hippocampal Slice by Inhibiting Presynaptic Glutamate Release in a Model of Temporal Lobe EpilepsyThe role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention.Overview of Glutamatergic Dysregulation in Central Pathologies.Parasynaptic NMDA receptor signaling couples neuronal glutamate transporter function to AMPA receptor synaptic distribution and stabilityGlutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformationGene profiling in temporal lobe epilepsy tissue and dysplastic lesions.Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.Genetic variation in neuronal glutamate transport genes and associations with posttraumatic seizure.Decreased glutamate transport enhances excitability in a rat model of cortical dysplasiaAbnormal expression of glutamate transporter and transporter interacting molecules in prefrontal cortex in elderly patients with schizophrenia.Seizure-like activity in hyaluronidase-treated dissociated hippocampal culturesSLC1 glutamate transportersNeuroprotective properties of the excitatory amino acid carrier 1 (EAAC1).Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease.Glutamatergic Mechanisms Associated with Seizures and Epilepsy.Mechanisms of Excessive Extracellular Glutamate Accumulation in Temporal Lobe Epilepsy.Cytogenesis in the dentate gyrus after neonatal hyperthermia-induced seizures: what becomes of surviving cells?Changes in Hippocampal Volume are Correlated with Cell Loss but Not with Seizure Frequency in Two Chronic Models of Temporal Lobe Epilepsy.New mechanism for glutamate hypothesis in epilepsy.Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus.Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model.Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats.Platelet uptake of GABA and glutamate in patients with bipolar disorder.Altered expression of neurotransmitter-receptor subunit and uptake site mRNAs in hemimegalencephaly.EAAC1 glutamate transporter expression in the rat lithium-pilocarpine model of temporal lobe epilepsy.Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Paraoxon.
P2860
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P2860
Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Increased expression of the ne ...... ampal and neocortical epilepsy
@ast
Increased expression of the ne ...... ampal and neocortical epilepsy
@en
type
label
Increased expression of the ne ...... ampal and neocortical epilepsy
@ast
Increased expression of the ne ...... ampal and neocortical epilepsy
@en
prefLabel
Increased expression of the ne ...... ampal and neocortical epilepsy
@ast
Increased expression of the ne ...... ampal and neocortical epilepsy
@en
P2093
P2860
P1433
P1476
Increased expression of the ne ...... ampal and neocortical epilepsy
@en
P2093
Amy R Brooks-Kayal
Melissa D Shumate
Michael B Robinson
Peter B Crino
P2860
P304
P356
10.1046/J.1528-1157.2002.35001.X
P577
2002-03-01T00:00:00Z