Allele and species dependent contractile defects by restrictive and hypertrophic cardiomyopathy-linked troponin I mutants
about
Cardiac troponin mutations and restrictive cardiomyopathyCell biology of sarcomeric protein engineering: disease modeling and therapeutic potentialLong term ablation of protein kinase A (PKA)-mediated cardiac troponin I phosphorylation leads to excitation-contraction uncoupling and diastolic dysfunction in a knock-in mouse model of hypertrophic cardiomyopathyPerturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutationsCombinatorial effects of double cardiomyopathy mutant alleles in rodent myocytes: a predictive cellular model of myofilament dysregulation in diseasePathogenic peptide deviations support a model of adaptive evolution of chordate cardiac performance by troponin mutations.Diastolic dysfunction and thin filament dysregulation resulting from excitation-contraction uncoupling in a mouse model of restrictive cardiomyopathy.Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathyMolecular determinants of cardiac myocyte performance as conferred by isoform-specific TnI residuesEffects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue.Sarcomere mutation-specific expression patterns in human hypertrophic cardiomyopathyFetal cardiac troponin isoforms rescue the increased Ca2+ sensitivity produced by a novel double deletion in cardiac troponin T linked to restrictive cardiomyopathy: a clinical, genetic, and functional approachInsights into restrictive cardiomyopathy from clinical and animal studies.Genetic Spectrum of Idiopathic Restrictive Cardiomyopathy Uncovered by Next-Generation SequencingA Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.Sarcomere neutralization in inherited cardiomyopathy: small-molecule proof-of-concept to correct hyper-Ca2+-sensitive myofilamentsPostischemic cardiac recovery in heme oxygenase-1 transgenic ischemic/reperfused mouse myocardium.Diverse Phenotypic Expression of Cardiomyopathies in a Family with TNNI3 p.Arg145Trp Mutation.Restrictive Cardiomyopathy Caused by Troponin Mutations: Application of Disease Animal Models in Translational StudiesMolecular mechanisms of sarcomere dysfunction in dilated and hypertrophic cardiomyopathy.Pediatric restrictive cardiomyopathy due to a heterozygous mutation of the TNNI3 gene.Restrictive Cardiomyopathy Troponin I R145W Mutation Does Not Perturb Myofilament Length-dependent Activation in Human Cardiac Sarcomeres.TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility.
P2860
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P2860
Allele and species dependent contractile defects by restrictive and hypertrophic cardiomyopathy-linked troponin I mutants
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Allele and species dependent c ...... athy-linked troponin I mutants
@ast
Allele and species dependent c ...... athy-linked troponin I mutants
@en
type
label
Allele and species dependent c ...... athy-linked troponin I mutants
@ast
Allele and species dependent c ...... athy-linked troponin I mutants
@en
prefLabel
Allele and species dependent c ...... athy-linked troponin I mutants
@ast
Allele and species dependent c ...... athy-linked troponin I mutants
@en
P2093
P2860
P1476
Allele and species dependent c ...... athy-linked troponin I mutants
@en
P2093
Haitao Wen
Jennifer Davis
Joseph M Metzger
Terri Edwards
P2860
P304
P356
10.1016/J.YJMCC.2008.02.274
P577
2008-02-26T00:00:00Z