Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons. - Wikidata - awgldk - TriplyDB

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

http://www.wikidata.org/entity/Q36749222

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Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3 Autophagy in airway diseases: a new frontier in human asthma?Canine hereditary ataxia in old english sheepdogs and gordon setters is associated with a defect in the autophagy gene encoding RAB24 Metacaspase Yca1 is required for clearance of insoluble protein aggregates.Disruption of neuronal autophagy by infected microglia results in neurodegeneration Sex-specific hippocampus-dependent cognitive deficits and increased neuronal autophagy in DEspR haploinsufficiency in mice Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons Activation of autophagy in a rat model of retinal ischemia following high intraocular pressure.Constitutive reactive oxygen species generation from autophagosome/lysosome in neuronal oxidative toxicity.An overview of the molecular mechanism of autophagy.C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy.Autophagy: a double-edged sword for neuronal survival after cerebral ischemia Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells Differences in the predominance of lysosomal and autophagic pathologies between infants and adults with Pompe disease: implications for therapy.Plant peroxisomes are degraded by starvation-induced and constitutive autophagy in tobacco BY-2 suspension-cultured cells.Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder--murine Pompe disease.Short-term fasting induces profound neuronal autophagy Autophagy is increased in postmortem brains of persons with HIV-1-associated encephalitis.Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure Basal Autophagy Is Required for Herpes simplex Virus-2 Infection Decreased autophagy: a major factor for cardiomyocyte death induced by β1-adrenoceptor autoantibodies.Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells.Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease.The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases.Genome-wide RNA-seq of iPSC-derived motor neurons indicates selective cytoskeletal perturbation in Brown-Vialetto disease that is partially rescued by riboflavin.Selective autophagy against membranous compartments: Canonical and unconventional purposes and mechanisms.Impaired mitochondrial homeostasis and neurodegeneration: towards new therapeutic targets?Advanced glycation end products (AGEs) induce apoptosis via a novel pathway: involvement of Ca2+ mediated by interleukin-8 protein.DAPK2 is a novel regulator of mTORC1 activity and autophagy.Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux.Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis.Sex differences in constitutive autophagy.Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.N-Acyldopamine induces aggresome formation without proteasome inhibition and enhances protein aggregation via p62/SQSTM1 expression.TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy

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Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

http://www.wikidata.org/entity/Q36749222

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

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type

label

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

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prefLabel

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

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Cell Death & Differentiation

P1476

Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons

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P2093

Kominami E

http://www.w3.org/2001/XMLSchema#string

Tanaka K

http://www.w3.org/2001/XMLSchema#string

Uchiyama Y

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Ueno T

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Waguri S

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P2860

The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

A ubiquitin-like system mediates protein lipidation.

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

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887-894

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scholarly article

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10.1038/SJ.CDD.4402120

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5

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14

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Masaaki Komatsu

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2007-03-02T00:00:00Z

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6473494

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17332773

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