Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. - Wikidata - awgldk - TriplyDB

Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease.

Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease.

http://www.wikidata.org/entity/Q36764094

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Current Research Therapeutic Strategies for Alzheimer's Disease Treatment β-Amyloid: the key peptide in the pathogenesis of Alzheimer's disease Amylin at the interface between metabolic and neurodegenerative disorders Neprilysin inhibition to treat heart failure: a tale of science, serendipity, and second chances Vitamin E, Turmeric and Saffron in Treatment of Alzheimer's Disease Neuroprotective Mechanisms Mediated by CDK5 Inhibition Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments.Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation.Effect of rosiglitazone on amyloid precursor protein processing and Aβ clearance in streptozotocin-induced rat model of Alzheimer's disease.Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways.Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer's disease Future Therapeutics in Alzheimer's Disease: Development Status of BACE Inhibitors.The effect of LCZ696 (sacubitril/valsartan) on amyloid-β concentrations in cerebrospinal fluid in healthy subjects Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2.Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction.Ex vivo 18O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.Neprilysin inhibition: A brief review of past pharmacological strategies for heart failure treatment and future directions.Role of Angiotensin Receptor-Neprilysin Inhibition in Heart Failure.Combining angiotensin II receptor 1 antagonism and neprilysin inhibition for the treatment of heart failure.proBDNF Accelerates Brain Amyloid-β Deposition and Learning and Memory Impairment in APPswePS1dE9 Transgenic Mice.Comparative Neuroprotective Effects of Dietary Curcumin and Solid Lipid Curcumin Particles in Cultured Mouse Neuroblastoma Cells after Exposure to Aβ42 Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex.Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis.Angiotensin Receptor-Neprilysin Inhibition.Exceptional in vivo catabolism of neurodegeneration-related aggregates.The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice.BACE1 cleaves APP(18-770) to APP(18-671) and APP(672-770)APP(672-713);APP(672-711) translocate from endosome lumen to extracellular region Contributions of neurotropic human herpesviruses herpes simplex virus 1 and human herpesvirus 6 to neurodegenerative disease pathology.Targeting Renin-Angiotensin System Against Alzheimer's Disease.Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders.APP translocates from plasma membrane to endosome lumen The Correlations of Plasma and Cerebrospinal Fluid Amyloid-Beta Levels with Platelet Count in Patients with Alzheimer's Disease

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Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease.

http://www.wikidata.org/entity/Q36764094

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2015 nî lūn-bûn

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Current Alzheimer Research

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Amyloid-beta protein clearance ...... r role in Alzheimer's disease.

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Debomoy K Lahiri

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Miguel A Pappolla

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Nigel H Greig

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Nipun Chopra

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Robert J Baranello

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P2860

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

Recognition of the polyubiquitin proteolytic signal

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.

The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

ApoE promotes the proteolytic degradation of Abeta

One step at a time: endoplasmic reticulum-associated degradation

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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1

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12

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Kumar Sambamurti

Krishna L Bharani

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Alzheimer's disease

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4820400

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