Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
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Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approachesGenetic and epigenetic studies of atopic dermatitisAtopic dermatitis: allergic dermatitis or neuroimmune dermatitis?Skin barrier defects in atopic dermatitisAtopic dermatitis in children: clinical features, pathophysiology, and treatmentExacerbation of allergen-induced eczema in TLR4- and TRIF-deficient mice.Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune responseTape Stripping Technique for Stratum Corneum Protein Analysis.Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes.Mutations in the Filaggrin are Predisposing Factor in Korean Children With Atopic Dermatitis.IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication.Food allergy: an enigmatic epidemic.Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis.New insights in the pathogenesis of atopic dermatitis.Cytokines and chemokines in irritant contact dermatitisGenome-wide association studies of atopic dermatitis.Recent advances in epidemiology and prevention of atopic eczema.The Genetics and Epigenetics of Atopic Dermatitis-Filaggrin and Other Polymorphisms.The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies.The association between phthalate exposure and atopic dermatitis with a discussion of phthalate induced secretion of interleukin-1β and thymic stromal lymphopoietin.Control of the Physical and Antimicrobial Skin Barrier by an IL-31-IL-1 Signaling Network.Skin barrier in atopic dermatitis: beyond filaggrin.Changes in cytokine profile may predict therapeutic efficacy of infliximab in patients with ulcerative colitis.iTRAQ-based quantitative proteomics of stratum corneum of dandruff scalp reveals new insights into its aetiology and similarities with atopic dermatitis.IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation.Risk factor-dependent dynamics of atopic dermatitis: modelling multi-scale regulation of epithelium homeostasis.Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis.Malassezia yeasts activate the NLRP3 inflammasome in antigen-presenting cells via Syk-kinase signalling.Spontaneous atopic dermatitis-like symptoms in a/a ma ft/ma ft/J flaky tail mice appear early after birth.Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus.Beneficial effects of melittin on ovalbumin-induced atopic dermatitis in mouse.IL-1β induces thymic stromal lymphopoietin and an atopic dermatitis-like phenotype in reconstructed healthy human epidermis.Atopic Eczema: Genetic Associations and Potential Links to Developmental Exposures.Measurement of skin surface biomakers by Transdermal Analyses Patch following different in vivo models of irritation: a pilot study.The effect of epidermal levels of urocanic acid on 25-hydroxyvitamin D synthesis and inflammatory mediators upon narrowband UVB irradiation.Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions.Primary atopic disorders.Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation.
P2860
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P2860
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@ast
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@en
type
label
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@ast
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@en
prefLabel
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@ast
Filaggrin loss-of-function mut ...... model of filaggrin deficiency.
@en
P2093
P2860
P50
P1476
Filaggrin loss-of-function mut ...... model of filaggrin deficiency
@en
P2093
Aileen Sandilands
Ellen S Koster
Gerwin J Puppels
Gráinne M O'Regan
Huijia Chen
Ivone Jakasa
Karin Kroboth
Linda E Campbell
Patrick M J H Kemperman
Peter Caspers
P2860
P304
P356
10.1016/J.JACI.2011.12.989
P407
P577
2012-02-08T00:00:00Z