Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.
about
Why we scratch an itch: the molecules, cells and circuits of itchThe functional and anatomical dissection of somatosensory subpopulations using mouse geneticsInhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade.New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?The cell biology of acute itchEvolving understanding on the aetiology of thermally provoked itchCalcitonin gene-related peptide: physiology and pathophysiologyActivation of mammalian target of rapamycin contributes to pain nociception induced in rats by BmK I, a sodium channel-specific modulatorNeural processing of itch.Three functionally distinct classes of C-fibre nociceptors in primates.Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells.Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations.Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms.The Troubled Touch of Autism.A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia.Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol.Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors.Protein kinase Cδ mediates histamine-evoked itch and responses in pruriceptorsDeletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord.Spatio-temporal expression and functional involvement of transient receptor potential vanilloid 1 in diabetic mechanical allodynia in rats.ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron SurvivalMolecular and cellular mechanisms that initiate pain and itch.Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation.Secreted herpes simplex virus-2 glycoprotein G alters thermal pain sensitivity by modifying NGF effects on TRPV1.Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature PreferenceThe role of calcitonin gene-related peptide in peripheral and central pain mechanisms including migraine.Calcium-permeable ion channels in pain signaling.Itch and nerve fibers with special reference to atopic dermatitis: therapeutic implications.Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control.Validation of ion channel targets.Cold Temperature Encoding by Cutaneous TRPA1 and TRPM8-Carrying Fibers in the Mouse.CGRP 8-37 enhances lipopolysaccharide-induced acute lung injury and regulating aquaporin 1 and 5 expressions in rats.Paclitaxel alters the evoked release of calcitonin gene-related peptide from rat sensory neurons in culture.The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch.Distinct calcitonin gene-related peptide expression pattern in primary afferents contribute to different neuropathic symptoms following chronic constriction or crush injuries to the rat sciatic nerve.Comprehensive thermal preference phenotyping in mice using a novel automated circular gradient assay.The lipid kinase PIP5K1C regulates pain signaling and sensitizationCiguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes NaV1.9, NaV1.7 and NaV1.1.Slick (Kcnt2) Sodium-Activated Potassium Channels Limit Peptidergic Nociceptor Excitability and Hyperalgesia.
P2860
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P2860
Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@ast
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@en
type
label
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@ast
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@en
prefLabel
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@ast
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@en
P2093
P2860
P1433
P1476
Peptidergic CGRPα primary sens ...... suppress sensitivity to cold.
@en
P2093
Alaine L Pribisko
Bonnie Taylor-Blake
Eric S McCoy
Jihong Zheng
Mark J Zylka
Sarah E Street
P2860
P304
P356
10.1016/J.NEURON.2013.01.030
P407
P577
2013-03-21T00:00:00Z