Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes
about
Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome.A placebo-controlled trial of simvastatin therapy in Smith-Lemli-Opitz syndrome.Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisionsPulmonary vein stenosis in patients with Smith-Lemli-Opitz syndrome.NIPBL+/- haploinsufficiency reveals a constellation of transcriptome disruptions in the pluripotent and cardiac states.Patient iPSCs: a new discovery tool for Smith-Lemli-Opitz syndrome.Spontaneously regressing brain lesions in Smith-Lemli-Opitz syndrome.
P2860
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P2860
Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@ast
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@en
type
label
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@ast
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@en
prefLabel
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@ast
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@en
P2093
P2860
P356
P1433
P1476
Modeling Smith-Lemli-Opitz syn ...... olesterol synthesis phenotypes
@en
P2093
Celine V Cluzeau
Christopher A Wassif
Forbes D Porter
Heiner Westphal
Kevin R Francis
Nasir Malik
Niraj S Trivedi
Peter E O'Halloran
Wonhwa Cho
P2860
P2888
P304
P356
10.1038/NM.4067
P407
P577
2016-03-21T00:00:00Z