Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
about
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenumMechanism and Treatment Strategy of Osteoporosis after TransplantationRole of Vitamin D in Osteoarthritis: Molecular, Cellular, and Clinical PerspectivesControl of bone mass and remodeling by PTH receptor signaling in osteocytesPotential role for therapies targeting DKK1, LRP5, and serotonin in the treatment of osteoporosisSingle-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibodyAltered bone remodeling in psoriatic arthritisWnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in miceEffects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin?Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease.Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis.Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo.The emerging role of serotonin (5-hydroxytryptamine) in the skeleton and its mediation of the skeletal effects of low-density lipoprotein receptor-related protein 5 (LRP5).Wnt-β-catenin signaling pathway inhibition by sclerostin may protect against degradation in healthy but not osteoarthritic cartilage.Serum Sclerostin Levels in Patients with Ankylosing Spondylitis and Rheumatoid Arthritis: A Systematic Review and Meta-AnalysisPharmacological management of osteogenesis.Anabolic therapies.Bone mineral density and serum biochemical predictors of bone loss in patients with CKD on dialysis.The effect of renal dysfunction on circulating sclerostin level in patients with type 2 diabetes.A cross-species analysis of a mouse model of breast cancer-specific osteolysis and human bone metastases using gene expression profiling.Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme.Update in serotonin and bone.Emerging therapeutic opportunities for skeletal restoration.Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal womenOxytocin and boneA roadmap to the brittle bones of cystic fibrosis.Sclerostin and Dickkopf-1 in renal osteodystrophy.Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells.Diseases affecting bone quality: beyond osteoporosis.Regulation of circulating sclerostin levels by sex steroids in women and in men.Serum Dickkopf-1 signaling and calcium deposition in aortic valve are significantly related to the presence of concomitant coronary atherosclerosis in patients with symptomatic calcified aortic stenosisParathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient micePTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.Relation of age, gender, and bone mass to circulating sclerostin levels in women and men.High serum levels of Dickkopf-1 are associated with a poor prognosis in prostate cancer patients.Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell culturesOsteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection.Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir.Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis
P2860
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P2860
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@ast
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@en
type
label
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@ast
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@en
prefLabel
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@ast
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@en
P356
P1433
P1476
Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
@en
P2093
Georges Rawadi
Roland Baron
P304
P356
10.1210/EN.2007-0270
P407
P577
2007-03-29T00:00:00Z