Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis. - Wikidata - awgldk - TriplyDB

Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis.

Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis.

http://www.wikidata.org/entity/Q36775480

about

The Foxc2 transcription factor regulates tumor angiogenesis Molecular mediators of angiogenesis.Targeting the PDGF signaling pathway in tumor treatment Pleiotropic stromal effects of vascular endothelial growth factor receptor 2 antibody therapy in renal cell carcinoma models.Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis.Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.Conditional ablation of macrophages disrupts ovarian vasculature.PDGF beta targeting in cervical cancer cells suggest a fine-tuning of compensatory signalling pathways to sustain tumourigenic stimulation Association between Regular Aspirin Use and Circulating Markers of Inflammation: A Study within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial Protective Effects of N-Acetyl Cysteine against Diesel Exhaust Particles-Induced Intracellular ROS Generates Pro-Inflammatory Cytokines to Mediate the Vascular Permeability of Capillary-Like Endothelial Tubes.Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome).AXL is an essential factor and therapeutic target for metastatic ovarian cancer Impaired angiogenesis in the enalapril-treated neonatal rat kidney.Pericytes on the tumor vasculature: jekyll or hyde?Clinicopathological and prognostic significance of galectin-1 and vascular endothelial growth factor expression in gastric cancer VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival Cytokines and angiogenesis in the corpus luteum Pericyte-fibroblast transition promotes tumor growth and metastasis.AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors Transcriptional targeting of tumor endothelial cells for gene therapy.Locally existing endothelial cells and pericytes in ovarian stroma, but not bone marrow-derived vascular progenitor cells, play a central role in neovascularization during follicular development in mice.Growth factors as active participants in carcinogenesis: a perspective.TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma.Molecular targeted therapy for hepatocellular carcinoma in the current and potential next strategies.Human blood-vessel-derived stem cells for tissue repair and regeneration.Cellular kinetics of perivascular MSC precursors.Heparan sulfate in angiogenesis: a target for therapy.Restoring TRAIL mediated signaling in ovarian cancer cells.Pericytes: a double-edged sword in cancer therapy.A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition.Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR) Axis as Target for Antitumor and Antiangiogenic Therapy.Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice.Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.The soluble VEGF receptor 1 and 2 expression in cerebral spinal fluid as an indicator for leukemia central nervous system metastasis.Spontaneous In Vivo Chondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells by Blocking Vascular Endothelial Growth Factor Signaling.Low differentiated microvascular density and low expression of platelet-derived growth factor-BB (PDGF-BB) predict distant metastasis and poor prognosis in clear cell renal cell carcinoma.CD11c+ M1-like macrophages (MΦs) but not CD206+ M2-like MΦ are involved in folliculogenesis in mice ovary.

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Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis.

http://www.wikidata.org/entity/Q36775480

description

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2008年論文

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2008年论文

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2008年论文

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name

Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Proceedings of the National Academy of Sciences of the United States of America

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Soluble receptor-mediated sele ...... ologic and tumor angiogenesis.

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Angeline Jocson

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Barbara Sennino

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Betty Y Y Tam

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Calvin J Kuo

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Donald M McDonald

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Frank Kuhnert

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Jenny Yuan

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John T Gray

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Nihar R Nayak

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Richard C Mulligan

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P2860

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Angiogenesis in the corpus luteum

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

Aberrant expression of PDGF ligands and receptors in the tumor prone ovary of follitropin receptor knockout (FORKO) mouse

Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities

Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

Angiogenesis in life, disease and medicine

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

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10185-10190

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10.1073/PNAS.0803194105

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29

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105

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51407143

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18632559

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2474564

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