Human cells compromised for p53 function exhibit defective global and transcription-coupled nucleotide excision repair, whereas cells compromised for pRb function are defective only in global repair.
about
Transcription Blockage Leads to New BeginningsTranscriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.Molecular characteristics of non-small cell lung cancer.Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.Impaired repair of cyclobutane pyrimidine dimers in human keratinocytes deficient in p53 and p63p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes.Interaction between the Cockayne syndrome B and p53 proteins: implications for agingThe tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosisMTA1 coregulator regulates p53 stability and function.UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cellsReciprocally regulated chromatin association of Cockayne syndrome protein B and p53 proteinCells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions.Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cellsThe role of DNA damage responses in p53 biology.Human cells bearing homozygous mutations in the DNA mismatch repair genes hMLH1 or hMSH2 are fully proficient in transcription-coupled nucleotide excision repair.The repair capacity of lung cancer cell lines A549 and H1299 depends on HMGB1 expression level and the p53 status.Repair of UV-induced thymine dimers is compromised in cells expressing the E6 protein from human papillomaviruses types 5 and 18.Optimal conditions to use Pfu exo(-) DNA polymerase for highly efficient ligation-mediated polymerase chain reaction protocols.Defective DNA repair and cell cycle arrest in cells expressing Merkel cell polyomavirus T antigen.Transcription-coupled repair is inducible in hamster cells.A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells.Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells.The p53-regulated cyclin-dependent kinase inhibitor, p21 (cip1, waf1, sdi1), is not required for global genomic and transcription-coupled nucleotide excision repair of UV-induced DNA photoproducts.Structural and functional involvement of p53 in BER in vitro and in vivo.p21(waf1/cip1)-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites.p53 is dispensable for UV-induced cell cycle arrest at late G(1) in mammalian cells.Richard B. Setlow, a commentary on seminal contributions and scientific controversies.Human cells deficient in p53 regulated p21(waf1/cip1) expression exhibit normal nucleotide excision repair of UV-induced DNA damage.P53 plays a protective role against UV- and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts.Polydeoxyribonucleotide promotes cyclobutane pyrimidine dimer repair in UVB-exposed dermal fibroblasts.Hesperidin promotes cyclobutane pyrimidine dimer repair in UVB-exposed mice epidermis.Human papillomavirus and genome instability: from productive infection to cancer
P2860
Q26801362-B3B9F380-FBC6-4519-A889-87FA7289E5CAQ30661634-93FAAB1B-FEB1-4E1A-9E40-79D10A2BCC92Q30782803-8651243F-C782-43CB-BFCA-083495881B61Q33600943-DFA09300-CC45-4630-AA3B-4204A9252275Q33772427-1B28E330-E945-432C-B49D-D4E78E3CCFC2Q33963455-6D6D3E5D-B13D-4E29-9AD6-3F340742AD13Q34258129-88BD0C12-285F-459A-A48E-DA179C987EC5Q34737062-6548E0DD-9DAC-4468-AC67-5A72395E4278Q35008387-48EF8A16-B14F-418A-90E7-2164C5B9CDA1Q35163378-0B9565E6-22A9-4C24-BDC2-F0F59C525434Q35266600-CB8C3F68-B514-41B8-9D45-83C556C811A9Q37263588-40A36AD6-AD32-401A-AD33-E9194600A5FFQ37271082-437E040C-D373-4DFC-BDEE-3797E033AB8EQ38331206-ECF2E03A-1D92-4218-839D-C9C3D610C5AEQ38363713-A48EFF6E-9183-41C7-B1E0-59A2DB2D9708Q38792514-FD1D12B6-4C25-4546-AF3D-55F3B46119A5Q38795632-23745930-A6F2-4872-9662-301E124CCCEAQ39097648-9A399EE5-61FE-4C82-9AB7-19F747B706BAQ39409460-14A47BCC-F027-4CF9-A441-1777B7896775Q39607390-813D1066-8E0A-4AEB-8556-272293E64716Q40033121-7B0A1C25-13FD-4A59-982B-5D591677D2A6Q40722141-7B4688C9-89C4-4EFD-AB33-985880E06088Q40809068-7E97D0B4-709B-47E8-888D-4DC94430B3AFQ40810976-D0DB91D3-49BC-4F9A-B91C-EBAB37CF769DQ40810986-CC43F6B5-3D6D-4484-99BC-0646FF42331AQ40815319-AD08B54E-91CB-4D3A-A7D8-ECBB62B92885Q43825651-361AE01B-45EE-43AE-948A-C334AFFB5EC4Q43918561-A13869F3-EC0B-4BBF-B688-8290F1BCC7C5Q44953358-F73ECC35-7A1A-4FF0-94D4-6446D02CE8BFQ46912321-EA83CD4C-EEC5-4BE3-AB54-DF49293D9EE0Q53291167-B32A626F-1A2D-4091-A854-ECABB211EDA9Q58699202-B4FC85AA-3CA4-4692-B4D9-B79F6221354C
P2860
Human cells compromised for p53 function exhibit defective global and transcription-coupled nucleotide excision repair, whereas cells compromised for pRb function are defective only in global repair.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Human cells compromised for p5 ...... fective only in global repair.
@ast
Human cells compromised for p5 ...... fective only in global repair.
@en
type
label
Human cells compromised for p5 ...... fective only in global repair.
@ast
Human cells compromised for p5 ...... fective only in global repair.
@en
prefLabel
Human cells compromised for p5 ...... fective only in global repair.
@ast
Human cells compromised for p5 ...... fective only in global repair.
@en
P2093
P2860
P356
P1476
Human cells compromised for p5 ...... fective only in global repair.
@en
P2093
E A Drobetsky
J P Therrien
P2860
P304
15038-15043
P356
10.1073/PNAS.96.26.15038
P407
P577
1999-12-01T00:00:00Z