about
A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent modelsThe history of African trypanosomiasisLeishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activitiesThe ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!Kinases as druggable targets in trypanosomatid protozoan parasitesHigh-resolution structures ofTrypanosoma bruceipteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug targetNew Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid ParasitesKilling of trypanosomatid parasites by a modified bovine host defense peptide, BMAP-18Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacinGenotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawalHigh prevalence of drug resistance in animal trypanosomes without a history of drug exposureSpecific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African TrypanosomiasisGenomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African TrypanosomeReduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPaseTransport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasisFacile Synthesis and Preliminary Structure-Activity Analysis of New Sulfonamides Against Trypanosoma bruceiIn vivo effect of Commiphora swynnertonii ethanolic extracts on Trypanosoma congolense and selected immunological components in miceSymmetrical choline-derived dications display strong anti-kinetoplastid activity.Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors: toward the development of novel therapies for African sleeping sickness.A fluorescence-based reporter substrate for monitoring RNA editing in trypanosomatid pathogensEffect of adjuvants on the humoral immune response to congopain in mice and cattle.Genetic dissection of drug resistance in trypanosomesGeneration of a nanobody targeting the paraflagellar rod protein of trypanosomesNaphthalene-based RNA editing inhibitor blocks RNA editing activities and editosome assembly in Trypanosoma bruceiTrypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomesPilot-scale compound screening against RNA editing identifies trypanocidal agents.New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.Temporizin and Temporizin-1 Peptides as Novel Candidates for Eliminating Trypanosoma cruzi.The molecular dynamics of Trypanosoma brucei UDP-galactose 4'-epimerase: a drug target for African sleeping sicknessTargeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategyLC-MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes.Trypanocidal action of bisphosphonium salts through a mitochondrial target in bloodstream form Trypanosoma bruceiAntiparasitic compounds that target DNA.Heterocyclic diamidine interactions at AT base pairs in the DNA minor groove: effects of heterocycle differences, DNA AT sequence and length.Assembly of the Trypanosoma brucei 60S ribosomal subunit nuclear export complex requires trypanosome-specific proteins P34 and P37.First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.
P2860
Q24612184-EDFA5A50-1D37-4E3C-B6ED-B62656AAA91CQ24650799-50CDF11E-B703-421D-9C18-DB6845BF26D5Q24655332-0E157F4E-B562-481D-B3E4-EE774E51561AQ26781588-05354CA6-0F13-4912-B1B7-1FCFAA79B5CEQ26786761-AC007486-A566-40D3-9E99-A5FAF4A891B2Q27666140-7B6B854F-8D04-4EF6-B232-058A5D9B7F1FQ28068159-5D6DE78C-B798-45A7-83A9-1D478A92D620Q28474642-94411439-8523-4E1D-AD62-F96060E04175Q28475606-18A6CA4F-8458-4C7D-AD9E-091F1C81D179Q28476222-125B41D8-ACE2-4655-A986-384BB80FC1BCQ28478493-3C306E53-AAB7-4A0D-9664-8B8322A57907Q28545788-0F57E7CA-CBAF-49BC-B8BF-ADCA4F2C9C7CQ28551770-43B56A44-A774-4828-85AB-007037825730Q28553507-EC85403F-0E0D-4196-8A8E-A85BD0271F4EQ28652499-A41ADB3D-2E74-498F-951B-4D5D367F6479Q33294205-058CB346-B454-4CEF-8EA8-3C0275ED12FFQ33535651-8E683B0F-2053-4168-B846-EC4939905E18Q33636542-9151CDD0-B949-4693-BC6E-E43F4C66FD7DQ33722744-C1AB471C-0E3C-4F65-9347-29B3CB96F023Q33747243-874F3419-626A-495D-A2B0-19592FD2E820Q33954211-22E2CF1E-321E-4BC1-829F-1DCFCC8E6B24Q34020275-2B800865-7D55-4BB0-A765-3B339583B974Q34279064-AE8B8039-423D-40A6-BAA1-86E94F9ECC52Q34647009-1B8ADD08-907A-4915-8FCD-127FBABC3E5FQ34796514-F5178EE7-F76E-4CE8-97F5-176BBD11BC2FQ34800149-3CCFF048-95EB-4B46-8B45-87D3ECC7839EQ34933034-A813303C-D23E-4E46-8618-C6ED315AC4F0Q34982034-BCFDE881-0560-40DD-8CBF-8BBAEC4B1E64Q35080508-F7EC0823-3561-40E2-AEA6-AB12CADFEC3FQ35234642-2DBD7349-F73B-45A2-ADF5-9087418F9804Q35822254-2C35F8F6-CACB-461A-8D5B-BF9125DBE254Q36069187-8A01A1C5-00C7-4043-85CA-A7B0E44A989BQ36103511-BF2986C4-67DC-4975-9F09-FB90FB73FA74Q36158447-94787687-BAF7-471D-B72B-D2016F36BDA4Q36162290-7A2B08A9-B32C-442E-AD1D-3EA2ADABC702Q36724059-D73CC6D7-C5C2-4FF4-A81F-894BC50C223BQ36835020-2BC42689-E195-45B8-AA9F-B160B53D09FEQ36916632-ADAC1C02-562A-4B82-A854-1925BB5B94EAQ37051206-39F5EF36-A7E7-404C-B5C0-123384ED5290Q37098728-EEFE7C3D-475B-4281-A9DC-964504F9D00A
P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Drugs and drug resistance in African trypanosomiasis.
@ast
Drugs and drug resistance in African trypanosomiasis.
@en
type
label
Drugs and drug resistance in African trypanosomiasis.
@ast
Drugs and drug resistance in African trypanosomiasis.
@en
prefLabel
Drugs and drug resistance in African trypanosomiasis.
@ast
Drugs and drug resistance in African trypanosomiasis.
@en
P1476
Drugs and drug resistance in African trypanosomiasis.
@en
P2093
Vincent Delespaux
P356
10.1016/J.DRUP.2007.02.004
P577
2007-02-01T00:00:00Z