Genetic mapping of the ability of Theiler's virus to persist and demyelinate.
about
Leader (L) and L* proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus' biological activitiesTheiler's virus infection: a model for multiple sclerosisA coding RNA sequence acts as a replication signal in cardiovirusesThree-dimensional structure of Theiler virus.Influence of the Theiler's virus L* protein on macrophage infection, viral persistence, and neurovirulence.An attenuated variant of the GDVII strain of Theiler's virus does not persist and does not infect the white matter of the central nervous systemDirect comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus.The neurovirulence of the DA and GDVII strains of Theiler's virus correlates with their ability To infect cultured neuronsThe GDVII strain of Theiler's virus spreads via axonal transport.The leader protein of Theiler's virus inhibits immediate-early alpha/beta interferon production.A spontaneous low-pathogenic variant of Theiler's virus contains an amino acid substitution within the predominant VP1(233-250) T-cell epitope.A determinant for central nervous system persistence localized in the capsid of Theiler's murine encephalomyelitis virus by using recombinant viruses.Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistenceBone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infectionInfection with Theiler's murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-kappaB activation: potential role for the initiation of demyelinating disease.Mutations that affect the tropism of DA and GDVII strains of Theiler's virus in vitro influence sialic acid binding and pathogenicity.Identification of a novel neuropathogenic Theiler's murine encephalomyelitis virus.Persistent poliovirus infection of human fetal brain cells.Role of VP2 amino acid 141 in tropism of Theiler's virus within the central nervous system.Major linear antibody epitopes and capsid proteins differentially induce protective immunity against Theiler's virus-induced demyelinating disease.The immune system preferentially clears Theiler's virus from the gray matter of the central nervous system.Importance of amino acid 101 within capsid protein VP1 for modulation of Theiler's virus-induced disease.Chimeric Theiler's virus with altered tropism for the central nervous systemAnalysis of antibody responses to predominant linear epitopes of Theiler's murine encephalomyelitis virus.A single amino acid change determines persistence of a chimeric Theiler's virus.Assembly of Theiler's virus recombinants used in mapping determinants of neurovirulence.Chimeric cDNA studies of Theiler's murine encephalomyelitis virus neurovirulence.Pathogenesis of early and late disease in mice infected with Theiler's virus, using intratypic recombinant GDVII/DA virusesDeterminants of persistence and demyelination of the DA strain of Theiler's virus are found only in the VP1 gene.The interaction of two groups of murine genes determines the persistence of Theiler's virus in the central nervous systemThe 5' noncoding sequences from a less virulent Theiler's virus dramatically attenuate GDVII neurovirulenceIntracerebral inoculation of mouse-passaged Saffold virus type 3 affects cerebellar development in neonatal mice.Infection of macrophage primary cultures by persistent and nonpersistent strains of Theiler's virus: role of capsid and noncapsid viral determinants.Role of sialyloligosaccharide binding in Theiler's virus persistence.Analysis of cellular mutants resistant to Theiler's virus infection: differential infection of L929 cells by persistent and neurovirulent strains.Amino acid substitutions in VP2 residues contacting sialic acid in low-neurovirulence BeAn virus dramatically reduce viral binding and spread of infection.Predominant binding of Theiler's viruses to a 34-kilodalton receptor protein on susceptible cell lines.Virus persistence in an animal model of multiple sclerosis requires virion attachment to sialic acid coreceptors
P2860
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P2860
Genetic mapping of the ability of Theiler's virus to persist and demyelinate.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Genetic mapping of the ability of Theiler's virus to persist and demyelinate.
@en
type
label
Genetic mapping of the ability of Theiler's virus to persist and demyelinate.
@en
prefLabel
Genetic mapping of the ability of Theiler's virus to persist and demyelinate.
@en
P2093
P2860
P1433
P1476
Genetic mapping of the ability of Theiler's virus to persist and demyelinate
@en
P2093
P2860
P304
P407
P577
1990-09-01T00:00:00Z